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Testing Data

Rabbit ADAM2 Polyclonal Antibody | anti-ADAM2 antibody

ADAM2 Antibody

Gene Names
ADAM2; CT15; FTNB; PH30; CRYN1; CRYN2; PH-30b; PH30-beta
Reactivity
Human
Predicted: Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
ADAM2; Polyclonal Antibody; ADAM2 Antibody; anti-ADAM2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
2547
Applicable Applications for anti-ADAM2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data
Related Product Information for anti-ADAM2 antibody
Rabbit polyclonal ADAM2 (1) antibody was raised against a recombinate human ADAM2 protein 411-653aa (BC034957).
References
(1) Ikawa, M., Nakanishi, T., Yamada, S., et al. Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertility. Dev. Biol. 240 (1), 254-261 (2001).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
80,158 Da
NCBI Official Full Name
Homo sapiens ADAM metallopeptidase domain 2, mRNA
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 2
NCBI Official Symbol
ADAM2
NCBI Official Synonym Symbols
CT15; FTNB; PH30; CRYN1; CRYN2; PH-30b; PH30-beta
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 2
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 2
UniProt Gene Name
ADAM2
UniProt Synonym Gene Names
FTNB; ADAM 2; CT15; PH30

NCBI Description

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Uniprot Description

Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.

Research Articles on ADAM2

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Product Notes

The ADAM2 adam2 (Catalog #AAA859141) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADAM2 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADAM2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20,000-1:80,000 WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the ADAM2 adam2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADAM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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