Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western Blot analysis of Human fetal muscle tissue and hela cell using ACTN3 Polyclonal Antibody at dilution of 1:400)

Rabbit anti-Human, Mouse ACTN3 Polyclonal Antibody | anti-ACTN3 antibody

ACTN3 Polyclonal Antibody

Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
affinity purification
Synonyms
ACTN3; Polyclonal Antibody; ACTN3 Polyclonal Antibody; anti-ACTN3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
affinity purification
Concentration
0.8mg/mL (varies by lot)
Sequence Length
944
Applicable Applications for anti-ACTN3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human ACTN3
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Human fetal muscle tissue and hela cell using ACTN3 Polyclonal Antibody at dilution of 1:400)

Western Blot (WB) (Western Blot analysis of Human fetal muscle tissue and hela cell using ACTN3 Polyclonal Antibody at dilution of 1:400)
Related Product Information for anti-ACTN3 antibody
This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants. The reference genome contains the non-coding allele. The non-functional allele of this gene is associated with elite athlete status.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
89
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
103 kDa
NCBI Official Full Name
alpha-actinin-3 isoform 2
NCBI Official Synonym Full Names
actinin, alpha 3 (gene/pseudogene)
NCBI Official Symbol
ACTN3
NCBI Protein Information
alpha-actinin-3; F-actin cross-linking protein; alpha-actinin skeletal muscle
UniProt Protein Name
Alpha-actinin-3
Protein Family
UniProt Gene Name
ACTN3
UniProt Entry Name
ACTN3_HUMAN

NCBI Description

This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. [provided by RefSeq, Feb 2014]

Uniprot Description

ACTN3: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Belongs to the alpha-actinin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: focal adhesion; actin filament; pseudopodium; cytosol

Molecular Function: integrin binding; protein binding; protein homodimerization activity; structural constituent of muscle; calcium ion binding; actin binding

Biological Process: focal adhesion formation; regulation of apoptosis; muscle filament sliding

Research Articles on ACTN3

Similar Products

Product Notes

The ACTN3 actn3 (Catalog #AAA2521186) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACTN3 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ACTN3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ACTN3 actn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACTN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.