Rabbit ACTL7A Polyclonal Antibody | anti-ACTL7A antibody

ACTL7A Rabbit Polyclonal

Cat. Num. AAA766351

• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: ACTL7A; Polyclonal Antibody; ACTL7A Rabbit Polyclonal; anti-ACTL7A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 435

• Applicable Applications for anti-ACTL7A antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
• Immunogen: Actin-like 7A
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(mouse testis tissue were subjected to SDS PAGE followed by western blot with MBS766351 (ACTL7A antibody) at dilution of 1:800)

NCBI and Uniprot Product Information

• NCBI GI #: 5729720
• NCBI GeneID: 10881
• NCBI Accession #: NP_006678.1
• NCBI GenBank Nucleotide #: NM_006687.3
• Molecular Weight: 48,644 Da
• NCBI Official Full Name: actin-like protein 7A
• NCBI Official Synonym Full Names: actin like 7A
• NCBI Official Symbol: ACTL7A
• NCBI Protein Information: actin-like protein 7A
• UniProt Protein Name: Actin-like protein 7A
• Protein Family: Actin-like protein
• UniProt Gene Name: ACTL7A
• UniProt Entry Name: ACL7A_HUMAN

NCBI Description

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known. [provided by RefSeq, Jul 2008]

Uniprot Description

AL7A: an actin-related protein (ARP). Shares significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. Its gene (ACTL7A), and a related gene, ACTL7B, are intronless. Expressed in a wide variety of adult tissues, however, its exact function is not known.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 9q31

Cellular Component: cytoplasm; cytoskeleton; Golgi apparatus; male germ cell nucleus; nucleus; protein complex

Molecular Function: protein binding; structural constituent of cytoskeleton