Rabbit CKAP4 Polyclonal Antibody | anti-CKAP4 antibody

CKAP4 Polyclonal Antibody

Cat. Num. AAA2519639

• Gene Names: CKAP4; p63; CLIMP-63; ERGIC-63
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: CKAP4; Polyclonal Antibody; CKAP4 Polyclonal Antibody; p63; CLIMP-63; ERGIC-63; anti-CKAP4 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 2.5mg/mL (varies by lot)
• Sequence Length: 602

• Applicable Applications for anti-CKAP4 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:1000-1:5000; IHC: 1:50-1:200
• Immunogen: Synthetic peptide of human CKAP4
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of 293T, hepG2 and A549 cell using CKAP4 Polyclonal Antibody at dilution of 1:1250)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human lung cancer using CKAP4 Polyclonal Antibody at dilution of 1:50)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer using CKAP4 Polyclonal Antibody at dilution of 1:50)

Related Product Information for anti-CKAP4 antibody

CKAP4 (cytoskeleton-associated protein 4), also known as p63, CLIMP-63 or ERGIC-63, is a 602 amino acid single-pass type II transmembrane protein that links the endoplasmic reticulum (ER) to the cytoskeleton. Considered a novel protein in maintaining ER morphology, CKAP4 anchors the ER to microtubles which is required for maintaining ER spatial distribution during interphase of the cell cycle. CKAP4 can be reversibly palmitoylated and phosphorylated and is a major substrate of the palmitoyl acyltransferase, ZDHHC2.

NCBI and Uniprot Product Information

• NCBI GI #: 19920317
• NCBI GeneID: 10970
• NCBI Accession #: NP_006816.2
• NCBI GenBank Nucleotide #: NM_006825.3
• Molecular Weight: 66,022 Da
• NCBI Official Full Name: cytoskeleton-associated protein 4
• NCBI Official Synonym Full Names: cytoskeleton-associated protein 4
• NCBI Official Symbol: CKAP4
• NCBI Official Synonym Symbols: p63; CLIMP-63; ERGIC-63
• NCBI Protein Information: cytoskeleton-associated protein 4; 63 kDa membrane protein; 63-kDa cytoskeleton-linking membrane protein; transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment; type-II transmembrane protein p63
• UniProt Protein Name: Cytoskeleton-associated protein 4
• Protein Family: Cytoskeleton-associated protein
• UniProt Gene Name: CKAP4
• UniProt Synonym Gene Names: Climp-63; p63
• UniProt Entry Name: CKAP4_HUMAN

Uniprot Description

CKAP4: High-affinity epithelial cell surface receptor for APF.

Protein type: Endoplasmic reticulum; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q23.3

Cellular Component: endoplasmic reticulum membrane; cytoskeleton; membrane; perinuclear region of cytoplasm; endoplasmic reticulum; plasma membrane; integral to membrane; lipid particle