Rabbit ACAT2 Polyclonal Antibody | anti-ACAT2 antibody

ACAT2 Rabbit Polyclonal

Cat. Num. AAA766305

• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: ACAT2; Polyclonal Antibody; ACAT2 Rabbit Polyclonal; anti-ACAT2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 426

• Applicable Applications for anti-ACAT2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunoprecipitation (IP)
• Immunogen: Acetyl-Coenzyme A acetyltransferase 2
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung using MBS766305 (ACAT2 antibody) at dilution of 1:100)

Testing Data

()

Western Blot (WB)

(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS766305 (ACAT2 antibody) at dilution of 1:2000)

NCBI and Uniprot Product Information

• NCBI GI #: 735997436
• NCBI GeneID: 39
• NCBI Accession #: NP_001290182.1
• NCBI GenBank Nucleotide #: NM_001303253.1
• Molecular Weight: 44,643 Da
• NCBI Official Full Name: acetyl-CoA acetyltransferase, cytosolic isoform 2
• NCBI Official Synonym Full Names: acetyl-CoA acetyltransferase 2
• NCBI Official Symbol: ACAT2
• NCBI Protein Information: acetyl-CoA acetyltransferase, cytosolic
• UniProt Protein Name: Acetyl-CoA acetyltransferase, cytosolic
• Protein Family: Acetyl-CoA acetyltransferase
• UniProt Gene Name: ACAT2
• UniProt Synonym Gene Names: ACTL
• UniProt Entry Name: THIC_HUMAN

NCBI Description

The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

Uniprot Description

ACAT2: The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. [provided by RefSeq, Jul 2008]

Protein type: Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Carbohydrate Metabolism - butanoate; EC 2.3.1.9; Acetyltransferase; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - propanoate; Lipid Metabolism - synthesis and degradation of ketone bodies; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; Lipid Metabolism - fatty acid

Chromosomal Location of Human Ortholog: 6q25.3

Cellular Component: cytoplasm; nucleolus; nucleus

Molecular Function: acetyl-CoA C-acetyltransferase activity; protein binding

Biological Process: lipid metabolic process

Disease: Acetyl-coa Acetyltransferase-2 Deficiency