Western Blot (WB)
(ABI2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ABI2 antibody detected the ABI2 protein (arrow).)
Rabbit anti-Human, mouse ABI2 Polyclonal Antibody | anti-ABI2 antibody
ABI2 Antibody (N-term)
Western Blot (WB)
(ABI2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ABI2 antibody detected the ABI2 protein (arrow).)
Western Blot (WB)
(ABI2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ABI2 antibody detected the ABI2 protein (arrow).)
Western Blot (WB)
(ABI2 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ABI2 antibody detected the ABI2 protein (arrow).)
Western Blot (WB)
(ABI2 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ABI2 antibody detected the ABI2 protein (arrow).)
Flow Cytometry (FC/FACS)
(ABI2 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(ABI2 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.)
Kano, S., et al. Cancer Res. 68(14):5572-5580(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Li, Y., et al. J. Cell. Sci. 120 (PT 8), 1436-1446 (2007) :
O'Donnell, C.J., et al. BMC Med. Genet. 8 SUPPL 1, S4 (2007) :
NCBI and Uniprot Product Information
Uniprot Description
Abi-2: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. Belongs to the ABI family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 2q33
Cellular Component: cytoskeleton; lamellipodium; cytoplasm; cytosol; filopodium
Molecular Function: protein binding; DNA binding; ubiquitin protein ligase binding; protein complex binding; Rac GTPase binding; cytoskeletal adaptor activity; kinase binding; SH3 domain binding
Biological Process: cell migration; peptidyl-tyrosine phosphorylation; actin polymerization and/or depolymerization; Rac protein signal transduction; cytoskeleton organization and biogenesis; cell motility
Research Articles on ABI2
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Product Notes
The ABI2 abi2 (Catalog #AAA9201003) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The ABI2 Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ABI2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the ABI2 abi2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABI2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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