Western Blot (WB)
(Western blot analysis of 5NT1A Antibody (N-term) in mouse heart tissue lysates (35ug/lane). 5NT1A (arrow) was detected using the purified Pab.)
Rabbit anti-Human, mouse 5NT1A Polyclonal Antibody | anti-NT5C1A antibody
5NT1A Antibody (N-term)
Western Blot (WB)
(Western blot analysis of 5NT1A Antibody (N-term) in mouse heart tissue lysates (35ug/lane). 5NT1A (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of 5NT1A Antibody (N-term) in mouse heart tissue lysates (35ug/lane). 5NT1A (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(5NT1A Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the 5NT1A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(5NT1A Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the 5NT1A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Lechward, K., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(4):280-284(2009)
Fyrberg, A., et al. Nucleosides Nucleotides Nucleic Acids 25 (9-11), 1201-1204 (2006) :
NCBI and Uniprot Product Information
NCBI Description
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008]
Uniprot Description
NT5C1A: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. Belongs to the 5'-nucleotidase type 3 family.
Protein type: Nucleotide Metabolism - pyrimidine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Nucleotide Metabolism - purine; Phosphatase (non-protein); EC 3.1.3.5
Chromosomal Location of Human Ortholog: 1p34.3-p33
Cellular Component: cytosol
Molecular Function: 5'-nucleotidase activity; nucleotide binding; magnesium ion binding
Biological Process: purine nucleoside monophosphate catabolic process; pyrimidine nucleoside catabolic process; pyrimidine base metabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; nucleoside metabolic process; purine nucleotide catabolic process; adenosine metabolic process; purine base metabolic process
Research Articles on NT5C1A
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Product Notes
The NT5C1A nt5c1a (Catalog #AAA9210570) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 91-119. The 5NT1A Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's 5NT1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the NT5C1A nt5c1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "5NT1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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