DNA-directed RNA polymerase III subunit RPC5 (Polr3e) Recombinant Protein | Polr3e recombinant protein
Recombinant Mouse DNA-directed RNA polymerase III subunit RPC5 (Polr3e)
Gene Names
Polr3e; Sin; RPC5
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
DNA-directed RNA polymerase III subunit RPC5 (Polr3e); Recombinant Mouse DNA-directed RNA polymerase III subunit RPC5 (Polr3e); Polr3e recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-710, Full length protein
Sequence
MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGMRDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSAPVGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGAELEAEEEEPMDTAPSTCLSTKLANGLPAGRAVGGDSLNGHPVPGCASNPVACELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHILFSGVSDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNLIQSRLTQECGEELSKQEVDKVLKDCCVSCGGMWYLKGTVQS
Sequence Length
710
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
76,860 Da
NCBI Official Full Name
DNA-directed RNA polymerase III subunit RPC5 isoform 2
NCBI Official Synonym Full Names
polymerase (RNA) III (DNA directed) polypeptide E
NCBI Official Symbol
Polr3e
NCBI Official Synonym Symbols
Sin; RPC5
NCBI Protein Information
DNA-directed RNA polymerase III subunit RPC5
UniProt Protein Name
DNA-directed RNA polymerase III subunit RPC5
Protein Family
UniProt Gene Name
Polr3e
UniProt Synonym Gene Names
Sin; RNA polymerase III subunit 5; RNA polymerase III subunit C5; Sxl interactor
Uniprot Description
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific periphjeric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway ().
Research Articles on Polr3e
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Product Notes
The Polr3e polr3e (Catalog #AAA1478626) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-710, Full length protein. The amino acid sequence is listed below: MANEEDDPVI QEIDVYLAKS LAEKLYLFQY PVRPASMTYD DIPHLSAKIK PKQQKVELEM AIDTLNPNYC RSKGEQIALN VDGACADETS TYSSKLMDKQ TFCSSQTTSN TARYAAALYR QGELHLTPLH GILQLRPSFS YLDKADAKHR EREAANEAGD SSQDEAEEDV KQITVRFSRP ESEQARQRRV QSYEFLQKKH AEEPWVHLHY YGMRDSRSEH ERQYLLCQGS SGVENTELVK SPSEYLMMLM PPSPEEEKDK PVAPSNVLSM AQLRTLPLAD QIKVLMKNVK VMPFANLMSL LGPSVDSVAV LRGIQKVAML VQGNWVVKSD ILYPKDSSSP HSGMPAEVLC RGRDFVMWKF TQSRWVVRKE VAAVTKLCAE DVKDFLEHMA VVRINKGWEF LLPYDLEFIK KHPDVVQRQH MLWSGIQAKL EKVYNLVKET MPKKPDGQSA PVGLVSGEQR VQTAKTKAQQ NHAFLERELQ RRKEQMRAAT VLPSVQIKEE PLSEEEADGA ELEAEEEEPM DTAPSTCLST KLANGLPAGR AVGGDSLNGH PVPGCASNPV ACELKAFVEA TFQRQFVLTL SELKRLFNLH LAGLPPGHIL FSGVSDRMLQ DTVLAAGCKQ ILVPFPPQTA ASPDEQKVFA LWESGDMSDQ HRQVLLEIFS KNYRVRRNLI QSRLTQECGE ELSKQEVDKV LKDCCVSCGG MWYLKGTVQS. It is sometimes possible for the material contained within the vial of "DNA-directed RNA polymerase III subunit RPC5 (Polr3e), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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