Mouse polymerase (DNA directed) kappa ELISA Kit | POLK elisa kit
Mouse DNA polymerase kappa, POLK ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
POLK: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Belongs to the DNA polymerase type-Y family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA repair, damage; DNA replication; EC 2.7.7.7; Transferase
Cellular Component: nucleoplasm; nucleus
Molecular Function: transferase activity; DNA binding; metal ion binding; DNA-directed DNA polymerase activity; damaged DNA binding; nucleotidyltransferase activity
Biological Process: nucleotide-excision repair, DNA gap filling; DNA replication; DNA repair; response to DNA damage stimulus
Research Articles on POLK
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Product Notes
The Mouse POLK polk (Catalog #AAA9316049) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316049 ELISA Kit recognizes Mouse POLK. It is sometimes possible for the material contained within the vial of "polymerase (DNA directed) kappa, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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