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Pronociceptin Recombinant Protein | PNOC recombinant protein
Recombinant Pronociceptin (PNOC)
Source: Prokaryotic expression
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- SLLSSVFSS CPRDCLTCQE KLHPAPDSFN LKTCILQCEE KVFPRPLWTV CTKVMASGSG QLSPADPELV SAALYQPKAS EMQHLKRMPR VRSLVQVRDA EPGADAEPGA DAEPGADDAE EVEQKQLQKR FGGFTGARKS ARKLANQKRF SEFMRQYLVL SMQSSQRRRT LHQNGNV
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
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NCBI and Uniprot Product Information
NCBI Description
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include nociceptin, nocistatin, and orphanin FQ2 (OFQ2). Nociceptin, also known as orphanin FQ, is a 17-amino acid neuropeptide that binds to the nociceptin receptor to induce increased pain sensitivity, and may additionally regulate body temperature, learning and memory, and hunger. Another product of the encoded preproprotein, nocistatin, may inhibit the effects of nociceptin. [provided by RefSeq, Jul 2015]
Uniprot Description
PNOC: Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. Belongs to the opioid neuropeptide precursor family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 8p21
Cellular Component: extracellular region
Molecular Function: neuropeptide hormone activity; protein binding; opioid peptide activity
Biological Process: synaptic transmission; neuropeptide signaling pathway; sensory perception; signal transduction
Research Articles on PNOC
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Product Notes
The PNOC pnoc (Catalog #AAA2029609) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic expression and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Pronociceptin can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the PNOC pnoc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.MGSSHHHHH H SSGLVPRGSH MASMTGGQQM GRGSEF- SLLSSVFSS CPRDCLTCQE KLHPAPDSFN LKTCILQCEE KVFPRPLWTV CTKVMASGSG QLSPADPELV SAALYQPKAS EMQHLKRMPR VRSLVQVRDA EPGADAEPGA DAEPGADDAE EVEQKQLQKR FGGFTGARKS ARKLANQKRF SEFMRQYLVL SMQSSQRRRT LHQNGNV. It is sometimes possible for the material contained within the vial of "Pronociceptin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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