Mouse pleckstrin homology domain containing, family O member 1 ELISA Kit | PLEKHO1 elisa kit
Mouse Pleckstrin homology domain-containing family O member 1, PLEKHO1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PLEKHO1: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT- mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor; Adaptor/scaffold
Cellular Component: membrane; cytoplasm; nucleus
Research Articles on PLEKHO1
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Product Notes
The Mouse PLEKHO1 plekho1 (Catalog #AAA9331890) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331890 ELISA Kit recognizes Mouse PLEKHO1. It is sometimes possible for the material contained within the vial of "pleckstrin homology domain containing, family O member 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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