Mouse Urokinase plasminogen activator surface receptor ELISA Kit | Plaur elisa kit
Mouse Urokinase plasminogen activator surface receptor ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
uPAR: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2. Expressed in neurons of the rolandic area of the brain. Expressed in the brain. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Receptor, misc.
Chromosomal Location of Human Ortholog: 7|7 A3
Cellular Component: cell surface; focal adhesion; integral to plasma membrane; plasma membrane
Molecular Function: enzyme binding; protein binding; protein domain specific binding; receptor binding; U-plasminogen activator receptor activity
Biological Process: mesenchymal cell differentiation; negative regulation of apoptosis; positive regulation of DNA binding; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of protein amino acid phosphorylation
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Product Notes
The Mouse Plaur plaur (Catalog #AAA9425228) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9425228 ELISA Kit recognizes Mouse Plaur. It is sometimes possible for the material contained within the vial of "Urokinase plasminogen activator surface receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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