Mouse Placental Lactogen ELISA Kit | PL elisa kit

Mouse Placental Lactogen ELISA Kit

Cat. Num. AAA45799

• Gene Names: CSH1; PL; CSA; CS-1; CSMT; hCS-A
• Reactivity: Mouse
• Synonyms: Placental Lactogen; Mouse Placental Lactogen ELISA Kit; PL elisa kit

• Reactivity: Mouse
• Specificity: No significant cross-reactivity or interference between Mouse PL and analogues was observed.

• Detection Range: 3.12ng/ml-100ng/ml
• Sensitivity: 1.0ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Inter-Assay: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of PL (hereafter termed "analyte") in undiluted original Mouse serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for PL elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! It is intended to be determinated PL concentrations in Mouse serum, plasma and other body fluids. Using Purified Mouse PL antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add PL and PL antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of PL in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 190034
• NCBI GeneID: 1442
• UniProt Accession #: P01243; Q0VDB1; Q14407
• Molecular Weight: 25,020 Da
• NCBI Official Full Name: placental lactogen
• NCBI Official Synonym Full Names: chorionic somatomammotropin hormone 1 (placental lactogen)
• NCBI Official Symbol: CSH1
• NCBI Official Synonym Symbols: PL; CSA; CS-1; CSMT; hCS-A
• NCBI Protein Information: chorionic somatomammotropin hormone; choriomammotropin; placental lactogen; chorionic somatomammotropin A
• UniProt Protein Name: Chorionic somatomammotropin hormone
• UniProt Gene Name: CSH1
• UniProt Synonym Gene Names: Choriomammotropin; PL
• UniProt Entry Name: CSH_HUMAN

NCBI Description

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]

Uniprot Description

CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: extracellular region

Molecular Function: metal ion binding; hormone activity