Pim 1 recombinant protein
Pim 1 protein
Purity
Pim 1 protein was purified using a a proprietary chromatographic technique.
Synonyms
Pim 1; Pim 1 protein; Serine/threonine-protein kinase Pim-1 protein; Pim protein; Pim-1 protein; Pim-1; Pim 1 recombinant protein
Host
Human
Purity/Purification
Pim 1 protein was purified using a a proprietary chromatographic technique.
Form/Format
Supplied in a storage buffer consisting of 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF and 25% glycerol
Protein Type
Recombinant
Biological Significance
The proto-oncogene Pim1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified from Moloney murine leukemia virus induced T-cell lymphomas in mice, Pim1 is involved in the control of cytokine-mediated cell proliferation, differentiation and survival of lymphoid and myeloid cells as well as others. Expression of Pim1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational and post-translational. Accumulating data support that the expression of Pim1 is mediated through activation of the JAK/STAT pathway. Some of the substrates of Pim1 include p21 Cip1, nuclear mitotic appartus protein, PTP-U2S and Socs-1.
Expression System
Sf-9 insect cells
Preparation and Storage
Store at -80 degree C
Related Product Information for Pim 1 recombinant protein
Purified recombinant Human Pim 1 protein
Product Categories/Family for Pim 1 recombinant protein
Similar Products
Product Notes
The Pim 1 (Catalog #AAA5303996) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Pim 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
