Human ATP-binding cassette sub-family B member 9 ELISA Kit | ABCB9 elisa kit

Human ATP-binding cassette sub-family B member 9 ELISA Kit

Cat. Num. AAA289162

• Gene Names: ABCB9; TAPL; EST122234
• Reactivity: Human
• Synonyms: ATP-binding cassette sub-family B member 9; Human ATP-binding cassette sub-family B member 9 ELISA Kit; ATP-binding cassette transporter 9; ABC transporter 9 protein; hABCB9; TAP-like protein; TAPL; ABCB9; KIAA1520; ABCB9 elisa kit

• Reactivity: Human
• Sequence Length: 703

• Assay Type: Sandwich
• Detection Range: 78-5000 pg/mL
• Sensitivity: 40.6 pg/mL
• Intra-Assay CV: <=5.0%
• Inter-Assay CV: <=6.3%
• Recovery: 96%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 339895785
• NCBI GeneID: 23457
• NCBI Accession #: NP_001229942.1
• NCBI GenBank Nucleotide #: NM_001243013.1
• UniProt Accession #: Q9NP78; Q5W9G7; Q769F3; Q769F4; Q96AB1; Q9P208; B4E2J0
• Molecular Weight: 77,470 Da
• NCBI Official Full Name: ATP-binding cassette sub-family B member 9 isoform 6
• NCBI Official Synonym Full Names: ATP binding cassette subfamily B member 9
• NCBI Official Symbol: ABCB9
• NCBI Official Synonym Symbols: TAPL; EST122234
• NCBI Protein Information: ATP-binding cassette sub-family B member 9
• UniProt Protein Name: ATP-binding cassette sub-family B member 9
• Protein Family: ABC transporter B family
• UniProt Gene Name: ABCB9
• UniProt Synonym Gene Names: KIAA1520; ABC transporter 9 protein; hABCB9; TAPL
• UniProt Entry Name: ABCB9_HUMAN

NCBI Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. [provided by RefSeq, Jul 2011]

Uniprot Description

ABCB9: ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transporter; Transporter, ABC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q24

Cellular Component: early endosome; endoplasmic reticulum; integral to endoplasmic reticulum membrane; integral to membrane; lysosomal membrane; lysosome

Molecular Function: ATP binding; oligopeptide-transporting ATPase activity; peptide-transporting ATPase activity; protein binding; protein homodimerization activity; substrate-specific transmembrane transporter activity

Biological Process: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; antigen processing and presentation of peptide antigen via MHC class I; metabolic process; peptide transport; positive regulation of antigen processing and presentation of peptide antigen via MHC class I; protein transport; transmembrane transport