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Peptidoglycan Recognition Protein 2 (PGLYRP2) Recombinant Protein | PGLYRP2 recombinant protein

Recombinant Peptidoglycan Recognition Protein 2 (PGLYRP2)

Gene Names
PGLYRP2; tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha
Applications
SDS-Page, Western Blot
Purity
> 95%
Synonyms
Peptidoglycan Recognition Protein 2 (PGLYRP2); Recombinant Peptidoglycan Recognition Protein 2 (PGLYRP2); HMFT0141; PGLYRPL; PGRP-L; PGRPL; TAGL-like; tagL; tagL-alpha; tagl-beta; N-acetylmuramoyl-L-alanine amidase; Peptidoglycan recognition protein long; PGLYRP2 recombinant protein
Ordering
For Research Use Only!
Host
E.coli
Purity/Purification
> 95%
Form/Format
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
Concentration
Original Concentration: 80ug/mL (varies by lot)
Applicable Applications for PGLYRP2 recombinant protein
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).
Organism Species
Homo sapiens (Human)
Source
Prokaryotic expression
Residues
Gln3~Gln236
Tags
N-terminal His Tag
Subcellular Location
Membrane, Secreted
Traits
Freeze-dried powder
Predicted isoelectric point
5.6
Usage
Reconstitute in ddH2O to a concentration of 0.1-1.0mg/mL. Do not vortex.
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 2-8°C for one month.
Aliquot and store at -80°C for 12 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for PGLYRP2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted Molecular Mass: 28.2kDa
Accurate Molecular Mass: 30kDa as determined by SDS-PAGE reducing conditions.
NCBI Official Full Name
N-acetylmuramoyl-L-alanine amidase
NCBI Official Synonym Full Names
peptidoglycan recognition protein 2
NCBI Official Symbol
PGLYRP2
NCBI Official Synonym Symbols
tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha
NCBI Protein Information
N-acetylmuramoyl-L-alanine amidase
UniProt Protein Name
N-acetylmuramoyl-L-alanine amidase
UniProt Gene Name
PGLYRP2
UniProt Synonym Gene Names
PGLYRPL; PGRPL; PGRP-L

NCBI Description

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]

Uniprot Description

PGLYRP2: May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.5.1.28; Hydrolase; Receptor, misc.; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19p13.12

Cellular Component: extracellular region; intracellular; membrane

Molecular Function: N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding; peptidoglycan receptor activity; zinc ion binding

Biological Process: antimicrobial humoral response; defense response to Gram-positive bacterium; detection of bacterium; innate immune response; negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation involved in immune response; pattern recognition receptor signaling pathway; peptide amidation; peptidoglycan catabolic process; regulation of inflammatory response

Research Articles on PGLYRP2

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Product Notes

The PGLYRP2 pglyrp2 (Catalog #AAA2097718) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Peptidoglycan Recognition Protein 2 (PGLYRP2) can be used in a range of immunoassay formats including, but not limited to, Positive Control; Immunogen; SDS-PAGE; Western Blot (WB). Researchers should empirically determine the suitability of the PGLYRP2 pglyrp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peptidoglycan Recognition Protein 2 (PGLYRP2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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