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SDS-PAGE

PDZD11 / PDZK11 / PISP recombinant protein

Recombinant Human PDZD11 / PDZK11 / PISP Protein (His tag)

Gene Names
PDZD11; PISP; AIPP1; PDZK11
Purity
> 97 % as determined by SDS-PAGE
Synonyms
PDZD11 / PDZK11 / PISP; Recombinant Human PDZD11 / PDZK11 / PISP Protein (His tag); RP13-26D14.3; AIPP1; PDZK11; PISP; PDZD11 / PDZK11 / PISP recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 97 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 8.0
Sequence Length
140
Application Notes
The recombinant human PDZD11 consisting of 146 amino acids and has a calculated molecular mass of 16.9 kDa. It migrates as an 18 kDa band in SDS-PAGE under reducing conditions as predicted.
Predicted N Terminal
Met
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for PDZD11 / PDZK11 / PISP recombinant protein
Background: PDZ domain-containing protein 11, also known as AIPP1a, PISP, PDZD11 and PDZK11, is a cytosolic protein which contains one PDZ (DHR) domain. PDZD11 bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. PDZD11 is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Full-length human PDZD11 shares 97% amino acids (aa) identity with mouse PDZD11.

Description: A DNA sequence encoding the human PDZD11 (NP_057568.1) (Asp 2-His 140) was expressed, with a polyhistide tag at the N-terminus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,492 Da
NCBI Official Full Name
PDZ domain-containing protein 11
NCBI Official Synonym Full Names
PDZ domain containing 11
NCBI Official Symbol
PDZD11
NCBI Official Synonym Symbols
PISP; AIPP1; PDZK11
NCBI Protein Information
PDZ domain-containing protein 11
UniProt Protein Name
PDZ domain-containing protein 11
UniProt Gene Name
PDZD11
UniProt Synonym Gene Names
AIPP1; PDZK11; PISP; PMCA-interacting single-PDZ protein

Uniprot Description

PDZD11: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: Xq13.1

Cellular Component: cytosol; intercellular junction; synapse

Molecular Function: protein binding

Biological Process: biotin metabolic process; exocytosis; maintenance of epithelial cell polarity; neurotransmitter secretion; pantothenate metabolic process; transmembrane transport

Research Articles on PDZD11 / PDZK11 / PISP

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Product Notes

The PDZD11 / PDZK11 / PISP pdzd11 (Catalog #AAA2545548) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The recombinant human PDZD11 consisting of 146 amino acids and has a calculated molecular mass of 16.9 kDa. It migrates as an 18 kDa band in SDS-PAGE under reducing conditions as predicted. Researchers should empirically determine the suitability of the PDZD11 / PDZK11 / PISP pdzd11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDZD11 / PDZK11 / PISP, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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