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Cyclic di-GMP phosphodiesterase yahA (yahA) Recombinant Protein | yahA recombinant protein

Recombinant Escherichia coli Cyclic di-GMP phosphodiesterase yahA (yahA)

Gene Names
yahA; ECK0313; JW0307
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Cyclic di-GMP phosphodiesterase yahA (yahA); Recombinant Escherichia coli Cyclic di-GMP phosphodiesterase yahA (yahA); yahA recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-362, full length protein
Sequence
MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTEISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGSNSHRYINDNHYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPDQFIPLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNLVNKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQAFPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKGVHFLQGYLYSPPVPGNKFISEWVMKAGG
Sequence Length
362
Species
Escherichia coli (strain K12)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,725 Da
NCBI Official Full Name
c-di-GMP-specific phosphodiesterase
NCBI Official Symbol
yahA
NCBI Official Synonym Symbols
ECK0313; JW0307
NCBI Protein Information
c-di-GMP-specific phosphodiesterase
UniProt Protein Name
Cyclic di-GMP phosphodiesterase PdeL
UniProt Gene Name
pdeL

NCBI Description

YahA has a C-terminal EAL domain, however, it lacks the GGDEF motif. [More information is available at EcoGene: EG11236]. Purified YahA exhibits c-di-GMP-specific phosphodiesterase activity. [More information is available at EcoCyc: EG11236].

Uniprot Description

Acts both as an enzyme and as a c-di-GMP sensor to couple transcriptional activity to the c-di-GMP status of the cell (PubMed:26553851). Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG (PubMed:15995192, PubMed:24451384, PubMed:26553851). Also acts as a transcription factor to control its own expression (PubMed:26553851).

Research Articles on yahA

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Product Notes

The yahA pdel (Catalog #AAA1084503) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-362, full length protein. The amino acid sequence is listed below: MNSCDFRVFL QEFGTTVHLS LPGSVSEKER LLLKLLMQGM SVTEISQYRN RSAKTISHQK KQLFEKLGIQ SDITFWRDIF FQYNPEIISA TGSNSHRYIN DNHYHHIVTP EAISLALENH EFKPWIQPVF CAQTGVLTGC EVLVRWEHPQ TGIIPPDQFI PLAESSGLIV IMTRQLMKQT ADILMPVKHL LPDNFHIGIN VSAGCFLAAG FEKECLNLVN KLGNDKIKLV LELTERNPIP VTPEARAIFD SLHQHNITFA LDDFGTGYAT YRYLQAFPVD FIKIDKSFVQ MASVDEISGH IVDNIVELAR KPGLSIVAEG VETQEQADLM IGKGVHFLQG YLYSPPVPGN KFISEWVMKA GG. It is sometimes possible for the material contained within the vial of "Cyclic di-GMP phosphodiesterase yahA (yahA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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