Sequence Information
Programmed Cell Death Protein 1 Recombinant Protein | PDCD1LG1 recombinant protein
Recombinant Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1)
Source: Prokaryotic expression
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- SNVTMEC RFPVEQKLDL LALVVYWEKE DKEVIQFVEG EEDLKPQHSS FRGRAFLPKD QLLKGNAVLQ ITDVKLQDAG VYCCMISYGG ADYKRITLKV NAPYRKINQR ISMDPATSEH ELMCQAEGYP EAEVIWTNSD HQSLSGETTV TTSQTEEKLL NVTSVLRVNA TANDVFHCTF WRVHSGENHT AELIIPELPV PRLPHNRTHW V
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Sequence Information
Sequence Information
SDS-Page
SDS-Page
Testing Data
Testing Data
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
Uniprot Description
PDCD1: a single-pass type I membrane protein. A negative regulator of activated T cells, is upregulated in human and mouse 'exhausted' T cells during persistent viral infection. A marker of angioimmunoblastic T-cell lymphoma and germinal center associated T cells.
Protein type: Membrane protein, integral; Apoptosis
Chromosomal Location of Human Ortholog: 2q37.3
Cellular Component: integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: signal transducer activity; protein binding
Biological Process: apoptosis; multicellular organismal development; T cell costimulation; signal transduction; humoral immune response
Disease: Systemic Lupus Erythematosus
Research Articles on PDCD1LG1
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Product Notes
The PDCD1LG1 pdcd1 (Catalog #AAA2031801) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic expression and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Programmed Cell Death Protein 1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the PDCD1LG1 pdcd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.MGSSHHHHH H SSGLVPRGSH MASMTGGQQM GRGSEF- SNVTMEC RFPVEQKLDL LALVVYWEKE DKEVIQFVEG EEDLKPQHSS FRGRAFLPKD QLLKGNAVLQ ITDVKLQDAG VYCCMISYGG ADYKRITLKV NAPYRKINQR ISMDPATSEH ELMCQAEGYP EAEVIWTNSD HQSLSGETTV TTSQTEEKLL NVTSVLRVNA TANDVFHCTF WRVHSGENHT AELIIPELPV PRLPHNRTHW V
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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