Proteasome-activating nucleotidase 1 (pan1) Recombinant Protein | pan1 recombinant protein
Recombinant Haloferax volcanii Proteasome-activating nucleotidase 1 (pan1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Proteasome-activating nucleotidase 1 (pan1); Recombinant Haloferax volcanii Proteasome-activating nucleotidase 1 (pan1); Proteasome-activating nucleotidase 1; PAN 1; Proteasomal ATPase 1; Proteasome regulatory ATPase 1; Proteasome regulatory particle 1; pan1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-406aa; full length protein
Sequence
MMTDTVDDVD LPYDKDSASQ QEKITALQER LEVLETQNEE MRDKLLDTNA ENNKYQQKLERLTHENKKLK QSPLFVATVQ EITDEGVIIK QHGNNQEALT EVTDEMREEL EPDARVAVNNSLSIVKRLDK ETDVRARVMQ VEHSPDVTYE DIGGLEEQMQ EVRETVEMPL DRPEMFAEVGIDPPSGVLLY GPPGTGKTML AKAVANQTNA SFIKMAGSEL VHKFIGEGAK LVRDLFEVARENEPAVIFID EIDAIASKRT DSKTSGDAEV QRTMMQLLAE MDGFDERGNI RIIAATNRFDMLDPAILRPG RFDRLIEVPK PNEDGREIIF QIHTRKMNVS DDVDFVELAE MADNASGADIKAVCTEAGMF AIRDDRTEIF MQDFVDAWEK IQQEASDETE VSRAFA
Sequence Length
406
Species
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for pan1 recombinant protein
pan1; panA
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,802 Da
NCBI Official Full Name
proteasome-activating nucleotidase A
NCBI Official Symbol
panA
NCBI Protein Information
proteasome-activating nucleotidase A
UniProt Protein Name
Proteasome-activating nucleotidase 1
Protein Family
UniProt Gene Name
pan1
UniProt Synonym Gene Names
PAN 1
UniProt Entry Name
PAN1_HALVD
Uniprot Description
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-terminus of the proteasomal ATPase functions like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates (Probable). Is also able to cleave other nucleoside triphosphates including GTP and TTP, but the rate of hydrolysis is 4- to 5-fold slower than for ATP.
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Product Notes
The pan1 pan1 (Catalog #AAA1180507) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-406aa; full length protein. The amino acid sequence is listed below: MMTDTVDDVD LPYDKDSASQ QEKITALQER LEVLETQNEE MRDKLLDTNA ENNKYQQKLE RLTHENKKLK QSPLFVATVQ EITDEGVIIK QHGNNQEALT EVTDEMREEL EPDARVAVNN SLSIVKRLDK ETDVRARVMQ VEHSPDVTYE DIGGLEEQMQ EVRETVEMPL DRPEMFAEVG IDPPSGVLLY GPPGTGKTML AKAVANQTNA SFIKMAGSEL VHKFIGEGAK LVRDLFEVAR ENEPAVIFID EIDAIASKRT DSKTSGDAEV QRTMMQLLAE MDGFDERGNI RIIAATNRFD MLDPAILRPG RFDRLIEVPK PNEDGREIIF QIHTRKMNVS DDVDFVELAE MADNASGADI KAVCTEAGMF AIRDDRTEIF MQDFVDAWEK IQQEASDETE VSRAFA. It is sometimes possible for the material contained within the vial of "Proteasome-activating nucleotidase 1 (pan1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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