Human purinergic receptor P2X, ligand-gated ion channel, 2 ELISA Kit | P2RX2 elisa kit
Human P2X purinoceptor 2, P2RX2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]
Uniprot Description
P2X2: Binding of this ligand-gated ion channel to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Belongs to the P2X receptor family. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, cation; Membrane protein, multi-pass; Channel, ligand-gated; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q24.33
Cellular Component: presynaptic membrane; cell surface; cell soma; integral to plasma membrane; postsynaptic density; apical plasma membrane; dendritic spine; terminal button; integral to nuclear inner membrane; receptor complex
Molecular Function: identical protein binding; copper ion binding; zinc ion binding; mercury ion binding; drug binding; ligand-gated ion channel activity; cadmium ion binding; ATP binding; phosphoinositide binding; cobalt ion binding; purinergic nucleotide receptor activity; nickel ion binding; ATP-gated cation channel activity
Biological Process: urinary bladder smooth muscle contraction; peristalsis; sensory perception of taste; protein heterooligomerization; generation of action potential; skeletal muscle fiber development; positive regulation of calcium-mediated signaling; detection of hypoxic conditions in blood by carotid body chemoreceptors; response to carbohydrate stimulus; response to ATP; behavioral response to pain; sensory perception of sound; response to hypoxia; neuromuscular synaptic transmission; protein homooligomerization; neuromuscular junction development
Disease: Deafness, Autosomal Dominant 41
Research Articles on P2RX2
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Product Notes
The Human P2RX2 p2rx2 (Catalog #AAA9339868) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339868 ELISA Kit recognizes Human P2RX2. It is sometimes possible for the material contained within the vial of "purinergic receptor P2X, ligand-gated ion channel, 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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