Oncostatin-M-specific receptor subunit beta (Osmr) Recombinant Protein | Osmr recombinant protein
Recombinant Rat Oncostatin-M-specific receptor subunit beta (Osmr), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Oncostatin-M-specific receptor subunit beta (Osmr); Recombinant Rat Oncostatin-M-specific receptor subunit beta (Osmr); partial; Osmr recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
29-738
Sequence
EP LQLTPEIHTV SLQSALQEAN LEWTVPTFSH QELNIVFQIE ISRMRTSNTI WVGNYSTTVK HEETVHWKWT SDIPLECATH FIRIRAMVDD AQYPPQSSWS NWSSWKEVNA QVSVPPDTLL IFPEDRLLEE GSNVTICLMI GQNLYNVSCK LQEEPIRGEQ LDSHLSLIKL NNVVFLNNAG TNINCKAMNG TKNTFGTVLF VSKVLEEPKN FSCETRDFKT LNCLWEPGID TTLSWHKQRS QHYTLYESFS GRREVSNHRN SHTWQITEDS QETYNFTLTA ENNLRKRSVS ISFNLTHRVH PKAPHDVTLK TVGATKAHMT WKVPSRGDYT LLCQVELQCE GEVIHEHNVS VHTSANYLFS DLEPDTEYKA CVRCASANHF WKWSDWMQKK FRTPEAAPSE ALDVWRDVRT ENGRHVVTLF WKPLLKSQAN GKIISYNIVV ENEANPTESE QYSVRAPALG TNLSLDLHPY KIHISANNSA GASPESLVVL SSHSGHEEVH EKTIKGIKNG FNISWEPVSG DAIGYVVDWC AHSQTQRCDL QWKNVGPNIT STIITSDAFE PGVRYNFRIF ERSVEENVRL VEKQRGYTQE LAPSVNPGVT IHNLTPNSFS LKWQDYASDF QSGFIKGYLV YLKSKELQCN PNWERTVLSD KSVLCKYDVD DPETKTLTVE NLRPESLYEF LVTPYTSAGQ GPNETYTKVT TPDVRSHM
Sequence Length
710
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Osmr recombinant protein
This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
108,625 Da
NCBI Official Full Name
oncostatin-M-specific receptor subunit beta
NCBI Official Synonym Full Names
oncostatin M receptor
NCBI Official Symbol
Osmr
NCBI Protein Information
oncostatin-M-specific receptor subunit beta
UniProt Protein Name
Oncostatin-M-specific receptor subunit beta
Protein Family
UniProt Gene Name
Osmr
UniProt Synonym Gene Names
Osmrb; IL-31 receptor subunit beta; IL-31R subunit beta; IL-31R-beta; IL-31RB
NCBI Description
mouse homolog binds cytokine signalling subunits c12 protein and gp130 and acts as a receptor for the cytokine oncostatin M [RGD, Feb 2006]
Uniprot Description
Associates with IL31RA to form the IL31 receptor. Binds IL31 and activates STAT1, STAT3 and STAT5. Capable of transducing OSM-specific signaling events (). The OSM/OSM-R system is pivotal in the differentiation of oval cells into hepatocytes, thereby promoting liver regeneration.
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Product Notes
The Osmr osmr (Catalog #AAA1377845) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 29-738. The amino acid sequence is listed below: EP LQLTPEIHTV SLQSALQEAN LEWTVPTFSH QELNIVFQIE ISRMRTSNTI WVGNYSTTVK HEETVHWKWT SDIPLECATH FIRIRAMVDD AQYPPQSSWS NWSSWKEVNA QVSVPPDTLL IFPEDRLLEE GSNVTICLMI GQNLYNVSCK LQEEPIRGEQ LDSHLSLIKL NNVVFLNNAG TNINCKAMNG TKNTFGTVLF VSKVLEEPKN FSCETRDFKT LNCLWEPGID TTLSWHKQRS QHYTLYESFS GRREVSNHRN SHTWQITEDS QETYNFTLTA ENNLRKRSVS ISFNLTHRVH PKAPHDVTLK TVGATKAHMT WKVPSRGDYT LLCQVELQCE GEVIHEHNVS VHTSANYLFS DLEPDTEYKA CVRCASANHF WKWSDWMQKK FRTPEAAPSE ALDVWRDVRT ENGRHVVTLF WKPLLKSQAN GKIISYNIVV ENEANPTESE QYSVRAPALG TNLSLDLHPY KIHISANNSA GASPESLVVL SSHSGHEEVH EKTIKGIKNG FNISWEPVSG DAIGYVVDWC AHSQTQRCDL QWKNVGPNIT STIITSDAFE PGVRYNFRIF ERSVEENVRL VEKQRGYTQE LAPSVNPGVT IHNLTPNSFS LKWQDYASDF QSGFIKGYLV YLKSKELQCN PNWERTVLSD KSVLCKYDVD DPETKTLTVE NLRPESLYEF LVTPYTSAGQ GPNETYTKVT TPDVRSHM. It is sometimes possible for the material contained within the vial of "Oncostatin-M-specific receptor subunit beta (Osmr), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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