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O-Sialoglycoprotein Endopeptidase Recombinant Protein | OSGEP recombinant protein

Recombinant Human O-Sialoglycoprotein Endopeptidase

Gene Names
OSGEP; KAE1; GCPL1; OSGEP1; PRSMG1
Purity
Greater than 80.0% as determined by SDS-PAGE.
Synonyms
O-Sialoglycoprotein Endopeptidase; Recombinant Human O-Sialoglycoprotein Endopeptidase; OSGEP Human; O-Sialoglycoprotein Endopeptidase Human Recombinant; T(6)A37 Threonylcarbamoyladenosine Biosynthesis Protein OSGEP; TRNA Threonylcarbamoyladenosine Biosynthesis Protein OSGEP; N6-L-Threonylcarbamoyladenine Synthase; T(6)A Synthase; HOSGEP; GCPL1; Probable TRNA Threonylcarbamoyladenosine Biosynthesis Protein OSGEP; Probable TRNA N6-Adenosine Threonylcarbamoyltransferase; Probable O-Sialoglycoprotein Endopeptidase; EC 3.4.24.57; EC 2.3.1.234; FLJ20411; OSGEP1; PRSMG1; KAE1; Probable tRNA N6-adenosine threonylcarbamoyltransferase; OSGEP recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE.
Form/Format
OSGEP protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMPAVLGF EGSANKIGVG VVRDGKVLAN PRRTYVTPPG TGFLPGDTARHHRAVILDLL QEALTESGLT SQDIDCIAYT KGPGMGAPLV SVAVVARTVA QLWNKPLVGV NHCIGHIEMGRLITGATSPT VLYVSGGNTQ VIAYSEHRYR IFGETIDIAVGNCLDRFARV LKISNDPSPG YNIEQMAKRG KKLVELPYTV KGMDVSFSGILSFIEDVAHR MLATGECTPE DLCFSLQETV FAMLVEITER AMAHCGSQEA LIVGGVGCNV RLQEMMATMCQERGARLFAT DERFCIDNGA MIAQAGWEMF RAGHRTPLSD SGVTQRYRTD EVEVTWRD.
Sequence Length
335
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Related Product Information for OSGEP recombinant protein
Introduction: O-Sialoglycoprotein Endopeptidase, also known as OSGEP is a member of the KAE1 / TsaD family. OSGEP is essential for the formation of threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs which read codons beginning with adenine. OSGEP take a direct catalytic part in the above reaction, however other proteins of the complex are required to fulfill this activity.

Description: OSGEP Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 358 amino acids (1-335 a.a) and having a molecular mass of 38.8kDa. OSGEP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for OSGEP recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,427 Da
NCBI Official Full Name
probable tRNA N6-adenosine threonylcarbamoyltransferase
NCBI Official Synonym Full Names
O-sialoglycoprotein endopeptidase
NCBI Official Symbol
OSGEP
NCBI Official Synonym Symbols
KAE1; GCPL1; OSGEP1; PRSMG1
NCBI Protein Information
probable tRNA N6-adenosine threonylcarbamoyltransferase
UniProt Protein Name
Probable tRNA N6-adenosine threonylcarbamoyltransferase
UniProt Gene Name
OSGEP
UniProt Synonym Gene Names
t(6)A synthase; hOSGEP
UniProt Entry Name
OSGEP_HUMAN

Uniprot Description

OSGEP: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Belongs to the KAE1 / YgjD family.

Protein type: EC 2.6.99.4; Protease

Chromosomal Location of Human Ortholog: 14q11.2

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Product Notes

The OSGEP osgep (Catalog #AAA141107) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMPA VLGF EGSANKIGVG VVRDGKVLAN PRRTYVTPPG TGFLPGDTAR HHRAVILDLL QEALTESGLT SQDIDCIAYT KGPGMGAPLV SVAVVARTVA QLWNKPLVGV NHCIGHIEMG RLITGATSPT VLYVSGGNTQ VIAYSEHRYR IFGETIDIAV GNCLDRFARV LKISNDPSPG YNIEQMAKRG KKLVELPYTV KGMDVSFSGI LSFIEDVAHR MLATGECTPE DLCFSLQETV FAMLVEITER AMAHCGSQEA LIVGGVGCNV RLQEMMATMC QERGARLFAT DERFCIDNGA MIAQAGWEMF RAGHRTPLSD SGVTQRYRTD EVEVTWRD. It is sometimes possible for the material contained within the vial of "O-Sialoglycoprotein Endopeptidase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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