ORP5 Blocking Peptide | OSBPL5 blocking peptide

ORP5 (OBPH1) Immunizing Peptide

Cat. Num. AAA425184

• Gene Names: OSBPL5; ORP5; OBPH1
• Reactivity: Human, Mouse, Rat, Dog
• Synonyms: ORP5; ORP5 (OBPH1) Immunizing Peptide; OSBPL5; OBPH1; FLJ31948; KIAA1534; DKFZp586H1719; oxysterol binding protein-like 5; OSBP-related protein 5; oxysterol-binding protein homologue 1; oxysterol-binding protein-related protein 5; FLJ42929; oxysterol-binding protein-like protein 5; ORP5 (OBPH1); OSBPL5 blocking peptide

• Reactivity: Human, Mouse, Rat, Dog
• Form/Format: 100ug of dried peptide
• Sequence: KEEAFLRRRFSLC
• Sequence Length: 879

• Preparation and Storage: Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 14149740
• NCBI GeneID: 114879
• NCBI Accession #: NP_065947.1; NP_663613.1; NP_001137535.1
• NCBI GenBank Nucleotide #: NM_020896.3
• Molecular Weight: 88,435 Da
• NCBI Official Full Name: oxysterol-binding protein-related protein 5 isoform a
• NCBI Official Synonym Full Names: oxysterol binding protein like 5
• NCBI Official Symbol: OSBPL5
• NCBI Official Synonym Symbols: ORP5; OBPH1
• NCBI Protein Information: oxysterol-binding protein-related protein 5
• UniProt Protein Name: Oxysterol-binding protein-related protein 5
• Protein Family: Oxysterol-binding protein-related protein
• UniProt Gene Name: OSBPL5
• UniProt Synonym Gene Names: ORP-5; OSBP-related protein 5
• UniProt Entry Name: OSBL5_HUMAN

NCBI Description

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]

Uniprot Description

OSBPL5: May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. Belongs to the OSBP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: cytosol; endoplasmic reticulum membrane; integral to membrane; membrane

Molecular Function: cholesterol binding; oxysterol binding; phosphatidylserine binding; phospholipid transporter activity

Biological Process: cholesterol metabolic process; cholesterol transport; Golgi to plasma membrane transport; phospholipid transport