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Sequence Information

Alpha-1-Acid Glycoprotein (a1AGP) Recombinant Protein | a1AGP recombinant protein

Recombinant Alpha-1-Acid Glycoprotein (a1AGP)

Gene Names
ORM1; ORM; AGP1; AGP-A
Reactivity
Human
Applications
SDS-Page, Western Blot
Purity
>97%
Synonyms
Alpha-1-Acid Glycoprotein (a1AGP); Recombinant Alpha-1-Acid Glycoprotein (a1AGP); a1AGP recombinant protein
Ordering
For Research Use Only!
Host
E. coli
Reactivity
Human
Purity/Purification
>97%
Form/Format
PBS, pH 7.4, containing 0.01% SKL
Concentration
Original Concentration: 200µg/mL (varies by lot)
Applicable Applications for a1AGP recombinant protein
Positive Control, Immunogen, SDS-PAGE, WB
(May be suitable for use in other assays to be determined by the end user.)
Source
Prokaryotic expression
Residues
Gln19~Ser201
Tags
N-terminal His-Tag
Tissue Specificity
Liver, Blood
Subcellular Location
Secreted
Traits
Freeze-dried powder
Predicted isoelectric point
5.5
Predicted Molecular Mass
23.1kDa
Accurate Molecular Mass
23kDa as determined by SDS-PAGE reducing conditions
Usage
Reconstitute in PBS (pH 7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8°C for one month.
Aliquot and store at -80°C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

Sequence Information

Sequence Information

SDS-Page

SDS-Page

Testing Data

Testing Data

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
alpha-1-acid glycoprotein 1
NCBI Official Synonym Full Names
orosomucoid 1
NCBI Official Symbol
ORM1
NCBI Official Synonym Symbols
ORM; AGP1; AGP-A
NCBI Protein Information
alpha-1-acid glycoprotein 1; AGP 1; OMD 1; orosomucoid-1
UniProt Protein Name
Alpha-1-acid glycoprotein 1
UniProt Gene Name
ORM1
UniProt Synonym Gene Names
AGP1; AGP 1; OMD 1
UniProt Entry Name
A1AG1_HUMAN

NCBI Description

This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]

Uniprot Description

ORM1: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding

Biological Process: regulation of immune system process; transport; acute-phase response; inflammatory response

Research Articles on a1AGP

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Product Notes

The a1AGP orm1 (Catalog #AAA2011236) is a Recombinant Protein produced from E. coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Alpha-1-Acid Glycoprotein (a1AGP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Alpha-1-Acid Glycoprotein (a1AGP) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, WB (May be suitable for use in other assays to be determined by the end user.) . Researchers should empirically determine the suitability of the a1AGP orm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Alpha-1-Acid Glycoprotein (a1AGP), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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