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Ornithine Decarboxylase Active Protein | ODC1 active protein
Ornithine Decarboxylase, Human Recombinant
Measure by its ability to catalyze 1.0 umole of ornithine to putrescine per minute at pH 7.6 and 37 degree C.
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Testing Data
(Fig A. Dose response kinetics of ODC with 2 mM Ornithine as the substrate. The amount of Putrescine generated per min as a function of Ornithine Decarboxylase was quantified using BioVision’s Total Polyamine Assay Kit (Please inquire). Fig B. The specific activity of Ornithine Decarboxylase is > 1 U/mg as assayed using BioVision’s Total Polyamine Assay Kit)
Testing Data
(Fig A. Dose response kinetics of ODC with 2 mM Ornithine as the substrate. The amount of Putrescine generated per min as a function of Ornithine Decarboxylase was quantified using BioVision’s Total Polyamine Assay Kit (Please inquire). Fig B. The specific activity of Ornithine Decarboxylase is > 1 U/mg as assayed using BioVision’s Total Polyamine Assay Kit)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]
Uniprot Description
ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]
Protein type: EC 4.1.1.17; Amino Acid Metabolism - arginine and proline; Other Amino Acids Metabolism - glutathione; Cell cycle regulation; Lyase
Chromosomal Location of Human Ortholog: 2p25
Cellular Component: cytoplasm; cytosol
Molecular Function: protein homodimerization activity; ornithine decarboxylase activity
Biological Process: response to virus; positive regulation of cell proliferation; regulation of protein catabolic process; kidney development; regulation of amino acid metabolic process; putrescine biosynthetic process from ornithine; polyamine metabolic process
Disease: Colorectal Cancer
Research Articles on ODC1
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Product Notes
The ODC1 odc1 (Catalog #AAA849966) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Ornithine Decarboxylase, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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