Rabbit anti-Human CFHR2 Polyclonal Antibody | anti-CFHR2 antibody

CFHR2 Antibody

Cat. Num. AAA1499581

• Gene Names: CFHR2; FHR2; HFL3; CFHL2
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >95%, Protein G purified
• Synonyms: CFHR2; Polyclonal Antibody; CFHR2 Antibody; Complement factor H-related protein 2 (FHR-2) (DDESK59) (H factor-like 3) (H factor-like protein 2); CFHL2 FHR2 HFL3; anti-CFHR2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 146

• Applicable Applications for anti-CFHR2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB:1:500-1:5000, IHC:1:20-1:200
• Conjugate: Non-conjugated
• Immunogen: Recombinant human Complement factor H-related protein 2 protein (20-269AA)
• Species: Human
• Research Area: Immunology
• Target Names: CFHR2
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: CFHR2 antibody at 2ug/mlLane 1:Hela whole cell lysateLane 2:293T whole cell lysateGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 31,28 kDaObserved band size: 36 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver tissue using MBS1499581 at dilution 1:100)

Related Product Information for anti-CFHR2 antibody

Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.

NCBI and Uniprot Product Information

• NCBI GI #: 916404479
• NCBI GeneID: 3080
• NCBI Accession #: NP_001299601.1
• NCBI GenBank Nucleotide #: NM_001312672.1
• UniProt Accession #: P36980; Q14310; Q5T9T1
• NCBI Official Full Name: complement factor H-related protein 2 isoform 2
• NCBI Official Synonym Full Names: complement factor H related 2
• NCBI Official Symbol: CFHR2
• NCBI Official Synonym Symbols: FHR2; HFL3; CFHL2
• NCBI Protein Information: complement factor H-related protein 2
• UniProt Protein Name: Complement factor H-related protein 2
• Protein Family: Complement factor H-related protein
• UniProt Gene Name: CFHR2
• UniProt Synonym Gene Names: CFHL2; FHR2; HFL3; FHR-2
• UniProt Entry Name: FHR2_HUMAN

NCBI Description

This gene belongs to a family of complement factor H-related genes (CFHR), which are clustered together with complement factor H gene on chromosome 1, and are involved in regulation of complement. Mutations in CFHR genes have been associated with dense deposit disease and atypical haemolytic-uraemic syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]

Uniprot Description

CFHR2: Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q31.3

Cellular Component: extracellular region