Mouse oligonucleotide/oligosaccharide-binding fold containing 2A ELISA Kit | OBFC2A elisa kit
Mouse SOSS complex subunit B2, OBFC2A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
OBFC2A: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. Belongs to the SOSS-B family. SOSS-B2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA repair, damage; Cell cycle regulation; DNA-binding
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: nucleic acid binding; DNA binding; RNA binding; single-stranded DNA binding
Biological Process: mitotic cell cycle checkpoint; response to ionizing radiation; DNA repair; response to DNA damage stimulus; double-strand break repair via homologous recombination
Research Articles on OBFC2A
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Product Notes
The Mouse OBFC2A nabp1 (Catalog #AAA9330550) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9330550 ELISA Kit recognizes Mouse OBFC2A. It is sometimes possible for the material contained within the vial of "oligonucleotide/oligosaccharide-binding fold containing 2A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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