ADP-sugar pyrophosphatase (Nudt5) Recombinant Protein | Nudt5 recombinant protein
Recombinant Mouse ADP-sugar pyrophosphatase (Nudt5)
NCBI and Uniprot Product Information
Uniprot Description
Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate (). In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10722730). Can also hydrolyze other nucleotide sugars with low activity (PubMed:10722730). In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate (). Nuclear ATP synthesis takes place when dephosphorylated at Thr-44 (). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (). Does not play a role in U8 snoRNA decapping activity (PubMed:21070968). Binds U8 snoRNA (PubMed:21070968).
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Product Notes
The Nudt5 nudt5 (Catalog #AAA1306196) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-218, full length protein. The amino acid sequence is listed below: METRESTESS PGKHLVTSEE LISEGKWVKF EKTTYMDPTG KTRTWETVKL TTRKGKSADA VSVIPVLQRT LHHECVILVK QFRPPMGSYC LEFPAGFIED GESPEAAALR ELEEETGYKG EVAECSPAVC MDPGLSNCTT HVVTVTINGD DAGNVRPKPK PGDGEFMEVI SLPKNDLLTR LDALGAEQHL TVDAKVYAYG LALKHANSKP FEVPFLKF. It is sometimes possible for the material contained within the vial of "ADP-sugar pyrophosphatase (Nudt5), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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