Nudix hydrolase 1 (NUDT1) Recombinant Protein | NUDT1 recombinant protein
Recombinant Arabidopsis thaliana Nudix hydrolase 1 (NUDT1)
NCBI and Uniprot Product Information
NCBI Description
Encodes a cytosol-localized nudix hydrolase that hydrolyzes 8-oxo-(d)GTP to its monophosphate form. This protective mechanism prevents the misincorporation of these oxidized nucleotides into DNA and RNA. NUDX1 also has a low level of dihydroneopterin triphosphate pyrophosphatase activity in vitro and may participate in the folate synthesis pathway.
Uniprot Description
Mediates the hydrolysis of some nucleoside diphosphate derivatives. Its substrate specificity is unclear. In vitro, it can use NTP, dNTP, 8-oxo-GTP, 8-oxo-dGTP, dGTP, dATP, dTTP or dihydroneopterin triphosphate (DHNTP) as substrate. Has some NADH pyrophosphatase activity in vitro; however, such activity may not be relevant in vivo due to the high concentration of manganese used during the experiments. Plays an important role in protection against oxidative DNA and RNA damage by removing oxidatively damaged form of guanine.
Research Articles on NUDT1
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Product Notes
The NUDT1 nudt1 (Catalog #AAA1462461) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-147, Full length protein. The amino acid sequence is listed below: MSTGEAIPRV AVVVFILNGN SILLGRRRSS IGNSTFALPG GHLEFGESFE ECAAREVMEE TGLKIEKMKL LTVTNNVFKE APTPSHYVSV SIRAVLVDPS QEPKNMEPEK CEGWDWYDWE NLPKPLFWPL EKLFGSGFNP FTHGGGD. It is sometimes possible for the material contained within the vial of "Nudix hydrolase 1 (NUDT1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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