Typical Testing Data/Standard Curve (for reference only)
Rat 7,8-dihydro-8-oxoguanine triphosphatase ELISA Kit | Nudt1 elisa kit
Rat 7,8-dihydro-8-oxoguanine triphosphatase ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
degrades 8-oxoguanine-containing deoxyribonucleoside triphosphate, a potentially mutagenic substrate for DNA synthesis; may control spontaneous mutagenesis [RGD, Feb 2006]
Uniprot Description
NUDT1: Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Belongs to the Nudix hydrolase family. 4 isoforms of the human protein are produced by alternative initiation.
Protein type: EC 3.6.1.55; EC 3.6.1.56; Hydrolase
Cellular Component: acrosome; cytoplasm; extracellular space; mitochondrial matrix; mitochondrion; nuclear membrane; nucleus; plasma membrane
Molecular Function: 8-oxo-7,8-dihydroguanine triphosphatase activity; ATP diphosphatase activity; m7G(5')pppN diphosphatase activity; snoRNA binding
Biological Process: aging; dATP catabolic process; dGTP catabolic process; DNA protection; male gonad development; purine nucleotide catabolic process; response to cadmium ion
Research Articles on Nudt1
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Product Notes
The Rat Nudt1 nudt1 (Catalog #AAA2882765) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882765 ELISA Kit recognizes Rat Nudt1. It is sometimes possible for the material contained within the vial of "7,8-dihydro-8-oxoguanine triphosphatase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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