Rat High affinity nerve growth factor receptor ELISA Kit | Ntrk1 elisa kit

Rat High affinity nerve growth factor receptor ELISA Kit

Cat. Num. AAA2883916

• Gene Names: Ntrk1; Trk
• Reactivity: Rat
• Synonyms: High affinity nerve growth factor receptor; Rat High affinity nerve growth factor receptor ELISA Kit; Neurotrophic tyrosine kinase receptor type 1; Slow nerve growth factor receptor; p140-TrkA; Trk-A; Ntrk1; Trk; Trka; 2.7.10.1; Ntrk1 elisa kit

• Reactivity: Rat
• Sequence Length: 799

• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 11024666
• NCBI GeneID: 59109
• NCBI Accession #: NP_067600.1
• NCBI GenBank Nucleotide #: NM_021589.1
• UniProt Accession #: P35739
• Molecular Weight: 87,252 Da
• NCBI Official Full Name: high affinity nerve growth factor receptor
• NCBI Official Synonym Full Names: neurotrophic tyrosine kinase, receptor, type 1
• NCBI Official Symbol: Ntrk1
• NCBI Official Synonym Symbols: Trk
• NCBI Protein Information: high affinity nerve growth factor receptor
• UniProt Protein Name: High affinity nerve growth factor receptor
• Protein Family: High affinity nerve growth factor receptor
• UniProt Gene Name: Ntrk1
• UniProt Synonym Gene Names: Trk; Trka; Trk-A
• UniProt Entry Name: NTRK1_RAT

NCBI Description

a protooncogene; receptor that binds to nerve growth factor (NGF) [RGD, Feb 2006]

Uniprot Description

TrkA: a receptor tyrosine kinase of the Trk family. High affinity receptor for nerve growth factor, neurotrophin-3 and neurotrophin-4/5 but not brain- derived neurotrophic factor. Known substrates include Shc, PI-3K, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system. Two splice variant isoforms have been described.

Protein type: Protein kinase, tyrosine (receptor); Kinase, protein; Oncoprotein; Membrane protein, integral; EC 2.7.10.1; Protein kinase, TK; TK group; Trk family

Cellular Component: axon; cell soma; cell surface; cytoplasm; cytoplasmic vesicle; dendrite; early endosome; early endosome membrane; Golgi membrane; integral to plasma membrane; late endosome; late endosome membrane; plasma membrane; protein complex; receptor complex

Molecular Function: ATP binding; GPI-linked ephrin receptor activity; kinase binding; nerve growth factor binding; nerve growth factor receptor activity; neurotrophin p75 receptor binding; protein binding; protein homodimerization activity; protein-tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity

Biological Process: activation of NF-kappaB transcription factor; aging; axon guidance; B cell differentiation; circadian rhythm; detection of mechanical stimulus involved in sensory perception of pain; detection of temperature stimulus involved in sensory perception of pain; ephrin receptor signaling pathway; learning and/or memory; mechanoreceptor differentiation; negative regulation of cell proliferation; negative regulation of neuron apoptosis; nerve growth factor receptor signaling pathway; nervous system development; olfactory nerve development; peptidyl-tyrosine phosphorylation; positive regulation of angiogenesis; positive regulation of GTPase activity; positive regulation of programmed cell death; positive regulation of protein amino acid phosphorylation; positive regulation of Ras protein signal transduction; positive regulation of synaptic transmission, glutamatergic; positive regulation of synaptogenesis; protein amino acid autophosphorylation; protein amino acid phosphorylation; response to activity; response to axon injury; response to drug; response to electrical stimulus; response to ethanol; response to hydrostatic pressure; response to nicotine; response to nutrient levels; response to radiation; sensory perception of pain; Sertoli cell development; sympathetic nervous system development