Putative methyltransferase NSUN4 (NSUN4) Recombinant Protein | NSUN4 recombinant protein

Recombinant Human Putative methyltransferase NSUN4 (NSUN4)

Cat. Num. AAA1280533

• Gene Names: NSUN4; SHTAP
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Putative methyltransferase NSUN4 (NSUN4); Recombinant Human Putative methyltransferase NSUN4 (NSUN4); NSUN4 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 26-384, Full length protein
• Sequence: RYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLWPSIRVSLLSEQKYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSPASWACSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQVGELVIPNLMANFGPMYFCKMRRLT
• Sequence Length: 359

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 371123153
• NCBI GeneID: 387338
• NCBI Accession #: NP_001243056.1
• NCBI GenBank Nucleotide #: NM_001256127.1
• UniProt Accession #: Q96CB9; Q5TDF7; Q96AN8; Q9HAJ8; A8K6S6; B3KQ50; B4DHA4
• Molecular Weight: 37,374 Da
• NCBI Official Full Name: 5-methylcytosine rRNA methyltransferase NSUN4 isoform b
• NCBI Official Synonym Full Names: NOP2/Sun RNA methyltransferase family member 4
• NCBI Official Symbol: NSUN4
• NCBI Official Synonym Symbols: SHTAP
• NCBI Protein Information: 5-methylcytosine rRNA methyltransferase NSUN4
• UniProt Protein Name: 5-methylcytosine rRNA methyltransferase NSUN4
• Protein Family: Sperm head and tail associated protein
• UniProt Gene Name: NSUN4

Uniprot Description

Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.