Probable histone-lysine N-methyltransferase NSD2 (Whsc1) Recombinant Protein | Whsc1 recombinant protein

Recombinant Mouse Probable histone-lysine N-methyltransferase NSD2 (Whsc1) , partial

• Gene Names: Nsd2; MMSET; Whsc1; Whsc1l; AW555663; mKIAA1090; 5830445G22Rik; 9430010A17Rik; C130020C13Rik; D030027O06Rik; D930023B08Rik
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Probable histone-lysine N-methyltransferase NSD2 (Whsc1); Recombinant Mouse Probable histone-lysine N-methyltransferase NSD2 (Whsc1); partial; Whsc1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 704

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Whsc1 recombinant protein

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

NCBI and Uniprot Product Information

• NCBI GI #: 295424164
• NCBI GeneID: 107823
• NCBI Accession #: NP_001074571.2
• NCBI GenBank Nucleotide #: NM_001081102.2
• UniProt Accession #: Q8BVE8; Q6ZPY1; Q7TSF5; Q811F0; B3VCH6
• Molecular Weight: 79,633 Da
• NCBI Official Full Name: histone-lysine N-methyltransferase NSD2 isoform 1
• NCBI Official Synonym Full Names: nuclear receptor binding SET domain protein 2
• NCBI Official Symbol: Nsd2
• NCBI Official Synonym Symbols: MMSET; Whsc1; Whsc1l; AW555663; mKIAA1090; 5830445G22Rik; 9430010A17Rik; C130020C13Rik; D030027O06Rik; D930023B08Rik
• NCBI Protein Information: histone-lysine N-methyltransferase NSD2
• UniProt Protein Name: Histone-lysine N-methyltransferase NSD2
• Protein Family: Histone-lysine N-methyltransferase
• UniProt Gene Name: Nsd2
• UniProt Synonym Gene Names: Kiaa1090; Whsc1; MMSET

Uniprot Description

Histone methyltransferase with histone H3 'Lys-27' (H3K27me) methyltransferase activity.