Neuritin Recombinant Protein | NRN1 recombinant protein

Recombinant Human Neuritin Protein

Cat. Num. AAA2556628

• Gene Names: NRN1; NRN; dJ380B8.2
• Purity: >95% as determined by reducing SDS-PAGE.
• Synonyms: Neuritin; Recombinant Human Neuritin Protein; NRN1; NRN; NRN1 recombinant protein

• Host: E Coli
• Purity/Purification: >95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 mum filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
• Sequence Length: 142

• Species: Human
• Endotoxin: <1.0 EU per ug as determined by LAL test.
• Fragment: Ala28-Gly116
• Fusion Tag: N-6His
• Preparation and Storage: Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.; Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.; Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.

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Related Product Information for NRN1 recombinant protein

Protein Construction: Recombinant Human Neuritin is produced by our E Coli expression system and the target gene encoding Ala28-Gly116 is expressed with a 6His tag at the N-terminus.

Background: Neuritin/NRN1 is a member of the neuritin family and can be expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. Neuritin/NRN1 promotes neurite outgrowt, arborization and neuritogenesis. The protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins.Overexpression of the encoded protein may be associated with astrocytoma progression.

NCBI and Uniprot Product Information

• NCBI GI #: 525314165
• NCBI GeneID: 51299
• NCBI Accession #: NP_001265639.1
• NCBI GenBank Nucleotide #: NM_001278710.1
• UniProt Accession #: Q9NPD7; Q7Z4Y1; B2RA93
• Molecular Weight: Molecular Mass: 12.1kDa; Actual Protein Molecular Mass: 10kDa
• NCBI Official Full Name: neuritin isoform 1
• NCBI Official Synonym Full Names: neuritin 1
• NCBI Official Symbol: NRN1
• NCBI Official Synonym Symbols: NRN; dJ380B8.2
• NCBI Protein Information: neuritin
• UniProt Protein Name: Neuritin
• Protein Family: Neuritin
• UniProt Gene Name: NRN1
• UniProt Synonym Gene Names: NRN

NCBI Description

This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.