Human neuritin 1 ELISA Kit | NRN1 elisa kit

Human Neuritin, NRN1 ELISA Kit

Cat. Num. AAA912929

• Gene Names: NRN1; NRN; dJ380B8.2
• Reactivity: Human
• Synonyms: neuritin 1; Human Neuritin; NRN1 ELISA Kit; Human Neuritin (NRN1) ELISA kit; MGC44811; NRN; dJ380B8.2; neuritin; NRN1 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of human NRN1. No significant cross-reactivity or interference between human NRN1 and analogues was observed.
• Sequence Length: 142

• Samples: Serum, plasma, tissue homogenates.
• Assay Type: Sandwich (Quantitative)
• Detection Range: 31.25 pg/ml-2000 pg/ml.
• Sensitivity: 7.81 pg/ml.
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
• Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for NRN1 elisa kit

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for NRN1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any NRN1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for NRN1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of NRN1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 525314165
• NCBI GeneID: 51299
• NCBI Accession #: NP_001265639.1
• NCBI GenBank Nucleotide #: NM_001278710.1
• UniProt Accession #: Q9NPD7; Q7Z4Y1; B2RA93
• Molecular Weight: 15,333 Da
• NCBI Official Full Name: neuritin isoform 1
• NCBI Official Synonym Full Names: neuritin 1
• NCBI Official Symbol: NRN1
• NCBI Official Synonym Symbols: NRN; dJ380B8.2
• NCBI Protein Information: neuritin
• UniProt Protein Name: Neuritin
• Protein Family: Neuritin
• UniProt Gene Name: NRN1
• UniProt Synonym Gene Names: NRN
• UniProt Entry Name: NRN1_HUMAN

NCBI Description

This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

NRN1: Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. Belongs to the neuritin family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 6p25.1

Cellular Component: plasma membrane; synapse; cell junction

Biological Process: nervous system development