Typical Testing Data/Standard Curve (for reference only)
Mouse Atrial natriuretic peptide receptor 1 ELISA Kit | Npr1 elisa kit
Mouse Atrial natriuretic peptide receptor 1 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
ANPA: natriuretic peptide receptor A, which mediates natriuretic, diuretic, and vasorelaxing actions of the natriuretic peptides. Contains five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Has guanylate cyclase activity on binding of ANF. Hypertensive SHR Rat has polymorphism at the locus. Human non-coding polymorphisms can alter expression up to two-fold, and have been associated with hypertension. A coding SNP is associated with hypertension and myocardial infarction.
Protein type: Protein kinase, dual-specificity (receptor); Lyase; Receptor, misc.; Kinase, protein; Membrane protein, integral; EC 4.6.1.2; Nucleotide Metabolism - purine; Guanylyl cyclase; Protein kinase, RGC; RGC group; RGC family
Cellular Component: guanylate cyclase complex, soluble; integral to membrane; membrane; plasma membrane; receptor complex
Molecular Function: ATP binding; GTP binding; guanylate cyclase activity; hormone binding; lyase activity; natriuretic peptide receptor activity; nucleotide binding; peptide hormone binding; phosphorus-oxygen lyase activity; protein kinase activity; protein kinase binding
Biological Process: cell surface receptor linked signal transduction; cGMP biosynthetic process; cyclic nucleotide biosynthetic process; dopamine metabolic process; negative regulation of smooth muscle cell proliferation; positive regulation of cGMP biosynthetic process; protein amino acid phosphorylation; receptor guanylyl cyclase signaling pathway; regulation of blood pressure; regulation of blood vessel size
Research Articles on Npr1
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Product Notes
The Mouse Npr1 npr1 (Catalog #AAA2885168) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885168 ELISA Kit recognizes Mouse Npr1. It is sometimes possible for the material contained within the vial of "Atrial natriuretic peptide receptor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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