Scavenger mRNA-decapping enzyme DcpS (nhm1) Recombinant Protein | nhm1 recombinant protein
Recombinant Schizosaccharomyces pombe Scavenger mRNA-decapping enzyme DcpS (nhm1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Scavenger mRNA-decapping enzyme DcpS (nhm1); Recombinant Schizosaccharomyces pombe Scavenger mRNA-decapping enzyme DcpS (nhm1); nhm1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-304, Full length
Sequence
MEESSAAKIQLLKEFKFEKILKDDTKSKIITLYGKIRNEVALLLLEKTAFDLNTIKLDQLATFLQDTKLVENNDVFHWFLSTNFQDCSTLPSVKSTLIWPASETHVRKYSSQKKRMVCETPEMYLKVTKPFIETQRGPQIQWVENILTHKAEAERIVVEDPDPLNGFIVIPDLKWDRQTMSALNLMAIVHATDIASIRDLKYKHIPLLENIRNKVLTEVPKQFSVDKNQLKMFVHYLPSYYHLHVHILHVDHETGDGSAVGRAILLDDVIDRLRNSPDGLENVNITFNIGEQHFLFQPLTNMNA
Sequence Length
304
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,107 Da
NCBI Official Full Name
m7G(5')pppN diphosphatase (predicted)
NCBI Official Symbol
nhm1
NCBI Protein Information
m7G(5')pppN diphosphatase (predicted)
UniProt Protein Name
m7GpppX diphosphatase
UniProt Gene Name
nhm1
UniProt Synonym Gene Names
dcps
Uniprot Description
Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP). Has no activity towards mRNA molecules longer than 25 nucleotides. May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCS1 to m7GMP. Inhibits mRNA translation. Binds to the m7GpppG cap analog.
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Product Notes
The nhm1 nhm1 (Catalog #AAA1459636) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-304, Full length. The amino acid sequence is listed below: MEESSAAKIQ LLKEFKFEKI LKDDTKSKII TLYGKIRNEV ALLLLEKTAF DLNTIKLDQL ATFLQDTKLV ENNDVFHWFL STNFQDCSTL PSVKSTLIWP ASETHVRKYS SQKKRMVCET PEMYLKVTKP FIETQRGPQI QWVENILTHK AEAERIVVED PDPLNGFIVI PDLKWDRQTM SALNLMAIVH ATDIASIRDL KYKHIPLLEN IRNKVLTEVP KQFSVDKNQL KMFVHYLPSY YHLHVHILHV DHETGDGSAV GRAILLDDVI DRLRNSPDGL ENVNITFNIG EQHFLFQPLT NMNA. It is sometimes possible for the material contained within the vial of "Scavenger mRNA-decapping enzyme DcpS (nhm1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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