Rabbit anti-Human AZI1 Polyclonal Antibody | anti-AZI1 antibody

AZI1 polyclonal antibody

Cat. Num. AAA3002875

• Gene Names: AZI1; AZ1; ZA1; Cep131
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: AZI1; Polyclonal Antibody; AZI1 polyclonal antibody; CEP131; KIAA1118; 5-azacytidine-induced protein 1; Centrosomal protein of 131 kDa; Cep131; Pre-acrosome localization protein 1; anti-AZI1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: AZI1 Polyclonal Antibody detects endogenous levels of AZI1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applicable Applications for anti-AZI1 antibody: Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)(paraffin section), ELISA (EIA)
• Application Notes: WB: 1/500-1/2000; IHC: 1/100-1/300; ELISA: 1/40,000
• Immunogen: The antiserum was produced against synthesized peptide derived from human AZI1. AA range: 311-360
• Function: May play a role in spermatogenesis.
• PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
• Similarity: Contains 1 IQ domain.
• Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
• Preparation and Storage: Store at 4 degee C for short term. Aliquot and store at -20 degee C long term. Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of various cells using AZI1 Polyclonal Antibody)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using AZI1 Antibody. The picture on the right is blocked with the synthesized peptide.)

Western Blot (WB)

(Western blot analysis of lysates from HUVEC cells, using AZI1 Antibody. The lane on the right is blocked with the synthesized peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 111955162
• NCBI GeneID: 22994
• NCBI Accession #: NP_001009811.2
• NCBI GenBank Nucleotide #: NM_001009811.2
• UniProt Accession #: Q9UPN4; Q96F50; A6NHI8; B2RN11
• Molecular Weight: 122,149 Da
• NCBI Official Full Name: 5-azacytidine-induced protein 1 isoform b
• NCBI Official Synonym Full Names: 5-azacytidine induced 1
• NCBI Official Symbol: AZI1
• NCBI Official Synonym Symbols: AZ1; ZA1; Cep131
• NCBI Protein Information: 5-azacytidine-induced protein 1; centrosomal protein 131 kDa; centrosomal protein of 131 kDa; pre-acrosome localization protein 1
• UniProt Protein Name: 5-azacytidine-induced protein 1
• Protein Family: pEARLI1-like lipid transfer protein
• UniProt Gene Name: AZI1
• UniProt Synonym Gene Names: CEP131; KIAA1118; Cep131
• UniProt Entry Name: AZI1_HUMAN

Uniprot Description

CEP131: a protein of the troponin family. Localized to the centrosome. Two alternatively-spliced isoforms have been described.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: nucleoplasm; centriole; microtubule cytoskeleton; centrosome; intercellular bridge; nuclear membrane; cell projection; intracellular membrane-bound organelle; acrosome; microtubule organizing center; nucleus; cytosol

Molecular Function: protein binding; protein homodimerization activity; protein complex binding

Biological Process: organelle organization and biogenesis; multicellular organismal development; positive regulation of cell proliferation; spermatogenesis; mitotic cell cycle; cell differentiation; G2/M transition of mitotic cell cycle