Cavy Neurofilament 3 ELISA Kit | NEF3 elisa kit
Cavy Neurofilament 3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Uniprot Description
NFM: a neurofilament intermediate filament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The levels of phosphorylation are altered developmentally and coincident with a change in the neurofilament function.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 8p21
Cellular Component: axon; neurofilament; neuromuscular junction
Molecular Function: protein binding; structural constituent of cytoskeleton; microtubule binding
Biological Process: neurofilament bundle assembly; axon cargo transport; regulation of axon diameter; microtubule cytoskeleton organization and biogenesis
Research Articles on NEF3
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Product Notes
The Cavy NEF3 nefm (Catalog #AAA057687) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA057687 ELISA Kit recognizes Cavy NEF3. It is sometimes possible for the material contained within the vial of "Neurofilament 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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