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Poliovirus receptor-related protein 1 (Pvrl1) Recombinant Protein | Pvrl1 recombinant protein

Recombinant Mouse Poliovirus receptor-related protein 1 (Pvrl1), partial

Gene Names
Nectin1; PRR; HIgR; HveC; PRR1; Cd111; Pvrl1; AI835281; AW549174; nectin-1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Poliovirus receptor-related protein 1 (Pvrl1); Recombinant Mouse Poliovirus receptor-related protein 1 (Pvrl1); partial; Pvrl1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
31-354
Sequence
QVVQVNDSMY GFIGTDVVLH CSFANPLPSV KITQVTWQKA SNGSKQNMAI YNPTMGVSVL PPYEKRVEFL RPSFIDGTIR LSGLELEDEG MYICEFATFP TGNRESQLNL TVMAKPTNWI EGTRAVLRAR KGQDDKVLVA TCTSANGKPP SAVSWETRLK GEAEYQEIRN PNGTVTVISR YRLVPSREAH RQSLACIVNY HLDRFRESLT LNVQYEPEVT IEGFDGNWYL QRTDVKLTCK ADANPPATEY HWTTLNGSLP KGVEAQNRTL FFRGPITYSL AGTYICEATN PIGTRSGQVE VNITEFPYTP TPEHGRRAGQ MPTA
Sequence Length
324
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Pvrl1 recombinant protein
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate
ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL
P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,035 Da
NCBI Official Full Name
nectin-1
NCBI Official Synonym Full Names
nectin cell adhesion molecule 1
NCBI Official Symbol
Nectin1
NCBI Official Synonym Symbols
PRR; HIgR; HveC; PRR1; Cd111; Pvrl1; AI835281; AW549174; nectin-1
NCBI Protein Information
nectin-1
UniProt Protein Name
Nectin-1
UniProt Gene Name
Nectin1
UniProt Synonym Gene Names
Herpesvirus entry mediator C; HveC

Uniprot Description

Involved in cell adhesion and synaptogegesis. Has some neurite outgrowth-promoting activity. Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells.

Research Articles on Pvrl1

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Product Notes

The Pvrl1 nectin1 (Catalog #AAA1389107) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 31-354. The amino acid sequence is listed below: QVVQVNDSMY GFIGTDVVLH CSFANPLPSV KITQVTWQKA SNGSKQNMAI YNPTMGVSVL PPYEKRVEFL RPSFIDGTIR LSGLELEDEG MYICEFATFP TGNRESQLNL TVMAKPTNWI EGTRAVLRAR KGQDDKVLVA TCTSANGKPP SAVSWETRLK GEAEYQEIRN PNGTVTVISR YRLVPSREAH RQSLACIVNY HLDRFRESLT LNVQYEPEVT IEGFDGNWYL QRTDVKLTCK ADANPPATEY HWTTLNGSLP KGVEAQNRTL FFRGPITYSL AGTYICEATN PIGTRSGQVE VNITEFPYTP TPEHGRRAGQ MPTA. It is sometimes possible for the material contained within the vial of "Poliovirus receptor-related protein 1 (Pvrl1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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