Rabbit PVRL1 Polyclonal Antibody | anti-PVRL1 antibody

PVRL1 Polyclonal Antibody

Cat. Num. AAA2563152

• Gene Names: NECTIN1; ED4; PRR; HIgR; HV1S; HVEC; OFC7; PRR1; PVRR; CD111; PVRL1; PVRR1; SK-12; CLPED1; nectin-1
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: PVRL1; Polyclonal Antibody; PVRL1 Polyclonal Antibody; CD111; CD111 antigen; CLPED1; Ectodermal dysplasia 4 (Margarita Island type); ED4; Herpes virus entry mediator C; Herpesvirus entry mediator C; Herpesvirus Ig like receptor; Herpesvirus Ig-like receptor; HIgR; HveC; MGC142031; Nectin 1; Nectin-1; OFC7; OROFACIAL CLEFT 7; OTTHUMP00000232093; OTTHUMP00000232094; OTTHUMP00000232095; Poliovirus receptor related protein 1; Poliovirus receptor-like 1; Poliovirus receptor-related protein 1; PRR; PRR1; PVRL 1; PVRR; PVRR1; SK-12; anti-PVRL1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 0.6mg/mL (varies by lot)
• Sequence Length: 517

• Applicable Applications for anti-PVRL1 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:25-1:100; ELISA: 1:1000-1:10000
• Immunogen: Synthetic peptide of human PVRL1
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human stomach cancer tissue using PVRL1 Polyclonal Antibody at dilution of 1:30(×200))

Related Product Information for anti-PVRL1 antibody

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

Product Categories/Family for anti-PVRL1 antibody

Cancer; Microbiology; Neuroscience

NCBI and Uniprot Product Information

• NCBI GI #: 42560237
• NCBI GeneID: 5818
• NCBI Accession #: NP_002846.3
• NCBI GenBank Nucleotide #: NP_002846.3
• UniProt Accession #: Q15223
• NCBI Official Full Name: nectin-1 isoform 1
• NCBI Official Synonym Full Names: nectin cell adhesion molecule 1
• NCBI Official Symbol: NECTIN1
• NCBI Official Synonym Symbols: ED4; PRR; HIgR; HV1S; HVEC; OFC7; PRR1; PVRR; CD111; PVRL1; PVRR1; SK-12; CLPED1; nectin-1
• NCBI Protein Information: nectin-1
• UniProt Protein Name: Poliovirus receptor-related protein 1
• UniProt Gene Name: PVRL1
• UniProt Synonym Gene Names: HVEC; PRR1; Herpesvirus entry mediator C; HveC; HIgR
• UniProt Entry Name: PVRL1_HUMAN

NCBI Description

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]