SDS-PAGE
NCR2 / NKp44 / CD336 recombinant protein
Recombinant Human NCR2 / NKp44 / CD336 Protein (His tag)
Gene Names
NCR2; LY95; CD336; NKP44; NK-p44; dJ149M18.1
Purity
> 88 % as determined by SDS-PAGE
Synonyms
NCR2 / NKp44 / CD336; Recombinant Human NCR2 / NKp44 / CD336 Protein (His tag); RP1-149M18.2; CD336; LY95; NK-p44; NKP44; dJ149M18.1; NCR2 / NKp44 / CD336 recombinant protein
Host
Human Cells
Purity/Purification
> 88 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
276
Application Notes
The secreted recombinant human NCR2 consists of 180 amino acids and has a calculated molecular mass of 20 kDa. The apparent molecular mass of the protein is approximately 37 kDa in SDS-PAGE under reducing conditions.
Predicted N Terminal
Gln 22
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for NCR2 / NKp44 / CD336 recombinant protein
Background: Natural cytotoxicity triggering receptor 2 (NCR2), also known as Natural killer cell p44-related protein (NKp44), or CD336, is a member of the natural cytotoxicity receptor (NCR) family, which composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. It is a novel transmembrane glycoprotein belonging to the Immunoglobulin superfamily characterized by a single extracellular V-type domain. The cytoplasmic domain of NKp44 also contains a sequence that matches the immunoreceptor tyrosine-based inhibitory motif (ITIM) consensus. This Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp44 is selectively expressed by IL-2-activated NK cells and may contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis. Tumor cell recognition of the mutated NKp44 proteins was significantly reduced and correlated with their lower recognition of heparin.
Description: A DNA sequence encoding the human NCR2 (NP_004819.2) extracellular domain (Met 1-Pro 190) was fused with a polyhistidine tag at the C-terminus.
Description: A DNA sequence encoding the human NCR2 (NP_004819.2) extracellular domain (Met 1-Pro 190) was fused with a polyhistidine tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,431 Da
NCBI Official Full Name
natural cytotoxicity triggering receptor 2 isoform 1
NCBI Official Synonym Full Names
natural cytotoxicity triggering receptor 2
NCBI Official Symbol
NCR2
NCBI Official Synonym Symbols
LY95; CD336; NKP44; NK-p44; dJ149M18.1
NCBI Protein Information
natural cytotoxicity triggering receptor 2
UniProt Protein Name
Natural cytotoxicity triggering receptor 2
UniProt Gene Name
NCR2
UniProt Synonym Gene Names
LY95; NK-p44; NKp44
Uniprot Description
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Research Articles on NCR2 / NKp44 / CD336
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Product Notes
The NCR2 / NKp44 / CD336 ncr2 (Catalog #AAA2545754) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The secreted recombinant human NCR2 consists of 180 amino acids and has a calculated molecular mass of 20 kDa. The apparent molecular mass of the protein is approximately 37 kDa in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the NCR2 / NKp44 / CD336 ncr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NCR2 / NKp44 / CD336, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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