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CEA native protein

CEA Ag(Preservative-free)

Applications
User optimized
Purity
>95% by SDS-PAGE and electrophoresis
Synonyms
CEA; CEA Ag(Preservative-free); Carcinoembryonic Antigen protein; CEA native protein
Ordering
For Research Use Only!
Purity/Purification
>95% by SDS-PAGE and electrophoresis
Form/Format
Purified by immunoaffinity column, supplied in 100mM PBS buffer, pH7.3 with no preservatives added.
Concentration
2.97 mg/mL by OD (varies by lot)
Sequence Length
702
Applicable Applications for CEA native protein
User optimized
Species
Human
Source
Metastatic liver, carcinoma, single patient
Protein Type
Native
Biological Significance
Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
Contaminants
Specifically depleted from mitgenic impurities
Biohazard
Tissue extract tested negative for HbsAg EIA, anti-HCV and anti-HIV1&2 EIA.
Preparation and Storage
Upon receipt store at -20°C. Avoid repeated freeze/thaw cycles
Related Product Information for CEA native protein
Purified native Human CEA protein (Preservative-free)
Product Categories/Family for CEA native protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
carcinoembryonic antigen
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 5
Protein Family
UniProt Gene Name
CEACAM5
UniProt Synonym Gene Names
CEA; CEA
UniProt Entry Name
CEAM5_HUMAN

Uniprot Description

Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.

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Product Notes

The CEA ceacam5 (Catalog #AAA539600) is a Native Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CEA can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the CEA ceacam5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEA, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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