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Typical Testing Data/Standard Curve (for reference only)

Mouse N-acetylaspartate synthetase ELISA Kit | Nat8l elisa kit

Mouse N-acetylaspartate synthetase ELISA Kit

Gene Names
Nat8l; Shati; 1110038O08Rik
Reactivity
Mouse
Synonyms
N-acetylaspartate synthetase; Mouse N-acetylaspartate synthetase ELISA Kit; NAA synthetase; N-acetyltransferase 8-like protein; Protein Shati; Nat8l; 2.3.1.17; Nat8l elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Sequence Length
299
Assay Type
Sandwich
Detection Range
0.156-10 ng/ml
Sensitivity
0.081 ng/mL
Intra-Assay CV
<=8.3%
Inter-Assay CV
<=9.8%
Recovery
89%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,777 Da
NCBI Official Full Name
N-acetylaspartate synthetase
NCBI Official Synonym Full Names
N-acetyltransferase 8-like
NCBI Official Symbol
Nat8l
NCBI Official Synonym Symbols
Shati; 1110038O08Rik
NCBI Protein Information
N-acetylaspartate synthetase
UniProt Protein Name
N-acetylaspartate synthetase
UniProt Gene Name
Nat8l
UniProt Synonym Gene Names
NAA synthetase
UniProt Entry Name
NAT8L_MOUSE

Uniprot Description

NAT8L: Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. Defects in NAT8L are the cause of N-acetylaspartate deficiency (NACED). A metabolic disorder resulting in truncal ataxia, marked developmental delay, seizures, and secondary microcephaly. Belongs to the camello family.

Protein type: Membrane protein, integral; Acetyltransferase; EC 2.3.1.17

Cellular Component: cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; intracellular membrane-bound organelle; membrane; mitochondrial membrane; mitochondrion

Molecular Function: aspartate N-acetyltransferase activity; N-acetyltransferase activity; transferase activity; transferase activity, transferring acyl groups

Biological Process: positive regulation of dopamine uptake

Research Articles on Nat8l

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Product Notes

The Mouse Nat8l nat8l (Catalog #AAA2880775) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880775 ELISA Kit recognizes Mouse Nat8l. It is sometimes possible for the material contained within the vial of "N-acetylaspartate synthetase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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