Interferon-induced GTP-binding protein Mx2 (Mx2) Recombinant Protein | Mx2 recombinant protein
Recombinant Mouse Interferon-induced GTP-binding protein Mx2 (Mx2)
Gene Names
Mx2; Mx-2; AI528743
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Interferon-induced GTP-binding protein Mx2 (Mx2); Recombinant Mouse Interferon-induced GTP-binding protein Mx2 (Mx2); Mx2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-655, Full length protein
Sequence
MVLSTEENTGVDSVNLPSGETGLGEKDQESVNNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLRKLNEGEEWRGKVSYDDIEVELSDPSEVEEAINKGQNFIAGVGLGISDKLISLDVSSPNVPDLTLIDLPGITRVAVGNQPADIGRQIKRLIKTYIQKQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDRGTEDKVVDVVRNLVYHLKKGYMIVKCRGQQDIQEQLSLTEALQNEQIFFKEHPHFRVLLEDGKATVPCLAERLTAELISHICKSLPLLENQIKESHQSASEELQKYGMDIPEDDSEKTFFLIEKINAFNQDITALVQGEENVAEGECRLFTRLRKEFLSWSKEIEKNFAKGYAVLYNEVWAFEKQYRGRELPGFVNYKTFENIIRRQIKTLEEPAIEMLHTVTEIVRAAFTSVSEKNFSEFYNLHRTTKSKLEDIRLEQEKEAEMSIRLHFKMEQIIYCQDQIYRGALQKVREEEAEEEKKTKHGTSSSSQSQDLQTSSMAEIFQHLNAYRQEAHNRISSHVPLIIQYFILKMFAERLQKGMLQLLQDKDSCSWLLKEQSDTSEKRKFLKERLARLAQARRRLAKFPG
Sequence Length
655
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Mx2 recombinant protein
This protein has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,292 Da
NCBI Official Full Name
interferon-induced GTP-binding protein Mx2
NCBI Official Synonym Full Names
MX dynamin-like GTPase 2
NCBI Official Symbol
Mx2
NCBI Official Synonym Symbols
Mx-2; AI528743
NCBI Protein Information
interferon-induced GTP-binding protein Mx2
UniProt Protein Name
Interferon-induced GTP-binding protein Mx2
Protein Family
UniProt Gene Name
Mx2
NCBI Description
This gene encodes a member of the Mx protein family of large GTPases, and functions in the innate immunity system. Interferon alpha/beta treatment or viral infection induces expression of this protein, which subsequently accumulates in the cytoplasm and inhibits viral replication. It has been shown to confer resistance to vesicular stomatitis virus, a member of the rhabdovirus family, but not to influenza virus. This gene produces a functional protein in some feral mouse strains, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a frameshift that inactivates this gene product. [provided by RefSeq, Jul 2008]
Uniprot Description
Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV) and Hantaan virus (HNTV).
Research Articles on Mx2
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Product Notes
The Mx2 mx2 (Catalog #AAA1290789) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-655, Full length protein. The amino acid sequence is listed below: MVLSTEENTG VDSVNLPSGE TGLGEKDQES VNNLCSQYEE KVRPCIDLID SLRALGVEQD LALPAIAVIG DQSSGKSSVL EALSGVALPR GSGIVTRCPL VLKLRKLNEG EEWRGKVSYD DIEVELSDPS EVEEAINKGQ NFIAGVGLGI SDKLISLDVS SPNVPDLTLI DLPGITRVAV GNQPADIGRQ IKRLIKTYIQ KQETINLVVV PSNVDIATTE ALSMAQEVDP EGDRTIGILT KPDLVDRGTE DKVVDVVRNL VYHLKKGYMI VKCRGQQDIQ EQLSLTEALQ NEQIFFKEHP HFRVLLEDGK ATVPCLAERL TAELISHICK SLPLLENQIK ESHQSASEEL QKYGMDIPED DSEKTFFLIE KINAFNQDIT ALVQGEENVA EGECRLFTRL RKEFLSWSKE IEKNFAKGYA VLYNEVWAFE KQYRGRELPG FVNYKTFENI IRRQIKTLEE PAIEMLHTVT EIVRAAFTSV SEKNFSEFYN LHRTTKSKLE DIRLEQEKEA EMSIRLHFKM EQIIYCQDQI YRGALQKVRE EEAEEEKKTK HGTSSSSQSQ DLQTSSMAEI FQHLNAYRQE AHNRISSHVP LIIQYFILKM FAERLQKGML QLLQDKDSCS WLLKEQSDTS EKRKFLKERL ARLAQARRRL AKFPG. It is sometimes possible for the material contained within the vial of "Interferon-induced GTP-binding protein Mx2 (Mx2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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