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Formamidopyrimidine-DNA glycosylase (mutM1) Recombinant Protein | mutM1 recombinant protein

Recombinant Xylella fastidiosa Formamidopyrimidine-DNA glycosylase (mutM1)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Formamidopyrimidine-DNA glycosylase (mutM1); Recombinant Xylella fastidiosa Formamidopyrimidine-DNA glycosylase (mutM1); mutM1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-271, Full length protein
Sequence
PELPEVETTLRGLLPYLTNQLIYSLTLRRRTLRWDIPSHIESRLPGHRITTVCRRAKYLLIDTNAGGSLIIHLGMSGTLRLLAPETPLRPHDHVDIMLNNRRVLRFNDPRRFGCLLWQEDGQIHPLLQRLGCEPLSDSFNGDYLYQCSRARNVSVKTFLMDQRIVVGVGNIYAAESLFRAGISPLCEADKISLQRYRRLAEVVKDILLYAINRGGTTLRDFLSPDGRPGYFKQELFVYGRQQQPCKQCGSLLRQTTIRQRTTVWCGHCQG
Sequence Length
270
Species
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31,091 Da
NCBI Official Full Name
formamidopyrimidine-DNA glycosylase
UniProt Protein Name
Formamidopyrimidine-DNA glycosylase
UniProt Gene Name
mutM1
UniProt Synonym Gene Names
fpg1; Fapy-DNA glycosylase; AP lyase MutM

Uniprot Description

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates ().

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Product Notes

The mutM1 mutm1 (Catalog #AAA1093056) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-271, Full length protein. The amino acid sequence is listed below: PELPEVETTL RGLLPYLTNQ LIYSLTLRRR TLRWDIPSHI ESRLPGHRIT TVCRRAKYLL IDTNAGGSLI IHLGMSGTLR LLAPETPLRP HDHVDIMLNN RRVLRFNDPR RFGCLLWQED GQIHPLLQRL GCEPLSDSFN GDYLYQCSRA RNVSVKTFLM DQRIVVGVGN IYAAESLFRA GISPLCEADK ISLQRYRRLA EVVKDILLYA INRGGTTLRD FLSPDGRPGY FKQELFVYGR QQQPCKQCGS LLRQTTIRQR TTVWCGHCQG. It is sometimes possible for the material contained within the vial of "Formamidopyrimidine-DNA glycosylase (mutM1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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