Translation initiation factor IF-2, mitochondrial (Mtif2) Recombinant Protein | Mtif2 recombinant protein

Recombinant Mouse Translation initiation factor IF-2, mitochondrial (Mtif2)

Cat. Num. AAA1420854

• Gene Names: Mtif2; IF-2mt; IF2(mt); IF-2(Mt); 2310038D14Rik; 2410112O06Rik
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Translation initiation factor IF-2; mitochondrial (Mtif2); Recombinant Mouse Translation initiation factor IF-2; Mtif2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 30-727, Full length protein
• Sequence: LAWCRHGFAPASSVWRDLLGARSWQTDMLIGSALHQHRLLVTKKEKRPPRSQLSPVKTKKEVEVWVGMTVEDLASAMAKDIDCVYEALLNTAIDVDSLEANSHLDEVWIKEVIKKAGMKLKWSKLKQERIRENKDAVRRPGTDPALLKPRSPVVTVMGHVDHGKTTLLDKLRETQVAAMEVGGITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAEVPIILAINKCDKTDADPEKVKKELLAYDVVCEEYGGDVQAVHVSALTGDNLMALAEATIALAEILELKADPTGPVEGTVIESFTDKGRGPVTTAIIQRGTLRKGSILVAGKSWAKVRLIFDENGKILNEAYPSMPVGIIGWRDLPSAGDEILEVESEPRAREVIEWRKSEQKEEKGKDDLKIMEEKRREHQEAHRKAREKYGSLHWKERSYIKFLERKQQRPLKPKEKVERQSNVLPIIIKGDVDGSVEAILNLLDTYDASHECELELVHFGLGDISENDVTFAETFDGVIYGFNVEAGSAIQQSAAQKGVKIKLHKIIYHLIEDLQEELSSRLPHTLEEYPIGEASILATFTVTEGKKKIPVAGCRVQKGQLERHKKFKLIRNGQVIWKGSLTSLKHHKDDISVIKTGMDCGLSLDEEKVEFKPGDQVICYEENKVPTKTSWDPGF
• Sequence Length: 698

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Mtif2 recombinant protein

During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. Two transcript variants encoding the same protein have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 530788297
• NCBI GeneID: 76784
• NCBI Accession #: NP_001269047.1
• NCBI GenBank Nucleotide #: NM_001282118.1
• UniProt Accession #: Q91YJ5; Q5M6W6
• Molecular Weight: 81,289 Da
• NCBI Official Full Name: translation initiation factor IF-2, mitochondrial isoform 1
• NCBI Official Synonym Full Names: mitochondrial translational initiation factor 2
• NCBI Official Symbol: Mtif2
• NCBI Official Synonym Symbols: IF-2mt; IF2(mt); IF-2(Mt); 2310038D14Rik; 2410112O06Rik
• NCBI Protein Information: translation initiation factor IF-2, mitochondrial
• UniProt Protein Name: Translation initiation factor IF-2, mitochondrial
• UniProt Gene Name: Mtif2
• UniProt Synonym Gene Names: IF-2(Mt); IF-2Mt; IF2(mt)

Uniprot Description

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex ().