Rabbit anti-Human MTIF2 Polyclonal Antibody | anti-MTIF2 antibody

MTIF2 Antibody

Cat. Num. AAA9430628

• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: MTIF2; Polyclonal Antibody; MTIF2 Antibody; anti-MTIF2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: The antibody detects endogenous levels of total MTIF2 protein.
• Purity/Purification: Antigen affinity purification
• Form/Format: pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: 0.6 mg/mL (varies by lot)
• Sequence Length: 727

• Applicable Applications for anti-MTIF2 antibody: Immunohistochemistry (IHC)
• Application Notes: IHC: 1:20-100
• Immunogen: Synthetic peptide of human MTIF2
• Immunogen Type: Peptide
• Preparation and Storage: Store at -20 degree C.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using 47646(MTIF2 Antibody) at dilution 1/20.(Original magnification: 200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 47646(MTIF2 Antibody) at dilution 1/20.(Original magnification: 200))

Related Product Information for anti-MTIF2 antibody

During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins.

Product Categories/Family for anti-MTIF2 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 53729339
• NCBI GeneID: 4528
• NCBI Accession #: NP_001005369.1
• NCBI GenBank Nucleotide #: NM_001005369.1
• UniProt Accession #: P46199; D6W5D0
• Molecular Weight: 81,317 Da
• NCBI Official Full Name: translation initiation factor IF-2, mitochondrial isoform a
• NCBI Official Synonym Full Names: mitochondrial translational initiation factor 2
• NCBI Official Symbol: MTIF2
• NCBI Protein Information: translation initiation factor IF-2, mitochondrial
• UniProt Protein Name: Translation initiation factor IF-2, mitochondrial
• UniProt Gene Name: MTIF2
• UniProt Synonym Gene Names: IF-2(Mt); IF-2Mt; IF2(mt)

NCBI Description

During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. [provided by RefSeq, Mar 2016]

Uniprot Description

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.