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Testing Data (The OmniKine Human Mesothelin ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Mesothelin proteins within the range of 250-8000 pg/ml.)

Human Mesothelin ELISA Kit | MSLN elisa kit

Mesothelin (Human) OmniKine ELISA Kit

Gene Names
MSLN; MPF; SMRP
Reactivity
Human
Synonyms
Mesothelin; Mesothelin (Human) OmniKine ELISA Kit; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor; MPF; MSLN elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
The OmniKine Human Mesothelin ELISA is capable of recognizing both recombinant and naturally produced Human Mesothelin proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: Mesothelin Propeptide (aa 35-289), MUC-1, MUC 16
Form/Format
12 x 8-Well Microstrips
Sequence Length
622
Samples
Plasma, serum, lysate
Assay Type
Sandwich ELISA
Detection Range
250-8000 pg/ml
Sensitivity
250-8000 pg/ml
Detection Method
Colorimetric 450 nm
Subtype
None
Preparation and Storage
Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Human Mesothelin ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Mesothelin proteins within the range of 250-8000 pg/ml.)

Testing Data (The OmniKine Human Mesothelin ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Mesothelin proteins within the range of 250-8000 pg/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67,940 Da
NCBI Official Full Name
mesothelin isoform 1 preproprotein
NCBI Official Synonym Full Names
mesothelin
NCBI Official Symbol
MSLN
NCBI Official Synonym Symbols
MPF; SMRP
NCBI Protein Information
mesothelin
UniProt Protein Name
Mesothelin
Protein Family
UniProt Gene Name
MSLN
UniProt Synonym Gene Names
MPF; MPF

NCBI Description

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Uniprot Description

MSLN: Membrane-anchored forms may play a role in cellular adhesion. Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. Belongs to the mesothelin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: cell surface; endoplasmic reticulum lumen; extracellular region; extracellular space; Golgi apparatus; membrane; plasma membrane

Molecular Function: protein binding

Biological Process: C-terminal protein lipidation; cell adhesion; cell-matrix adhesion; cellular protein metabolic process; pancreas development; post-translational protein modification

Research Articles on MSLN

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Product Notes

The Human MSLN msln (Catalog #AAA9502062) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502062 ELISA Kit recognizes Human MSLN. It is sometimes possible for the material contained within the vial of "Mesothelin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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